SCHEMBL679222

SCHEMBL679222

O=C(Nc1ccc(O)cc1)c1ccccc1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DEGS1 O15121 1/20 0.79
POLB P06746 3/20 0.78
KDM4E B2RXH2 2/20 0.78
PTPN1 P18031 2/20 0.74
NPC1 O15118 5/20 0.71
RAB9A P51151 5/20 0.71
MEN1 O00255 2/20 0.71
KMT2A Q03164 2/20 0.71
SIRT1 Q96EB6 1/20 0.71
MAPT P10636 1/20 0.69
SMN1; SMN2 Q16637 1/20 0.69
CACNA1B Q00975 1/20 0.67
APBA1 Q02410 1/20 0.67
TDP1 Q9NUW8 2/20 0.66
CTDSP1 Q9GZU7 1/20 0.66
NQO2 P16083 1/20 0.66
PRMT1 Q99873 1/20 0.65
FFAR1 O14842 1/20 0.65
PGR P06401 1/20 0.65
MAOA P21397 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11688443 0.98 DEGS1 (0.83) DEGS1POLBKDM4EPTPN1NPC1
SCHEMBL7112688 0.93 DEGS1 (0.93) DEGS1POLBKDM4EPTPN1NPC1
N-Phenylbenzamide SCHEMBL27671345 0.92 POLB (0.71) DEGS1POLBKDM4EPTPN1NPC1
SCHEMBL1603641 0.92 DEGS1 (0.79) DEGS1POLBKDM4EPTPN1NPC1
SCHEMBL126415 0.91 PTPN1 (0.87) POLBKDM4EPTPN1NPC1RAB9A
SCHEMBL8420639 0.89 DEGS1 (0.75) DEGS1POLBKDM4EPTPN1NPC1
SCHEMBL899585 0.89 DEGS1 (0.75) DEGS1POLBKDM4EPTPN1NPC1
SCHEMBL900928 0.89 DEGS1 (0.75) DEGS1POLBKDM4EPTPN1NPC1
SCHEMBL14715824 0.89 NPC1 (0.88) POLBKDM4EPTPN1NPC1RAB9A
SCHEMBL18103163 0.89 NPC1 (0.88) POLBKDM4EPTPN1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 265 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210332001-A1 SYNTHESIS AND ANTI-TUMOR ACTIVITIES OF ACYL-PARA-AMINOPHENOL DERIVATIVES MONTEFIORE MEDICAL CENTER 2021-10-28 US claimed
CN-102702013-B Nuclear receptor binding agents GTX INC. (US) 2016-02-10 CN claimed
US-9161542-B2 Pesticidal compositions and related methods DOW AGROSCIENCES LLC (US) 2015-10-20 US claimed
WO-2012162595-A2 PESTICIDAL COMPOSITIONS AND RELATED METHODS DOW AGROSCIENCES LLC (US) 2012-11-29 WO claimed
US-20120302611-A1 PESTICIDAL COMPOSITIONS AND RELATED METHODS DOW AGROSCIENCES LLC (US) 2012-11-29 US claimed
US-8187788-B2 Photosensitive resin composition and photosensitive film ASAHI KASEI KABUSHIKI KAISHA (JP) 2012-05-29 US claimed
US-20090191385-A1 Photosensitive Resin Composition and Photosensitive Film ASAHI KASEI KABUSHIKI KAISHA (JP) 2009-07-30 US claimed
CN-101336227-A Nuclear receptor binding agents GTX INC (US) 2008-12-31 CN claimed
CN-1633290-A Mono-and bicyclic pyrrole derivatives inhibiting ligand interaction with higher glycation end product receptors TRANSTECH PHARMA INC (US) 2005-06-29 CN claimed
EP-0409313-A2 Poly carbonates endowed with high-fluidity characteristics and process for preparing them ENICHEM S.p.A. (IT) 1991-01-23 EP claimed
US-4517005-A Aminophenol urease inhibitors and urease inhibited urea based fertilizer compositions ALLIED CORPORATION (US) 1985-05-14 US claimed
US-3968140-A PROSTAGLANDINS THE UPJOHN COMPANY (US) 1976-07-06 US claimed
US-3952048-A PROSTAGLANDINS THE UPJOHN COMPANY (US) 1976-04-20 US claimed
US-3931281-A PROSTAGLANDINS THE UPJOHN COMPANY (US) 1976-01-06 US claimed
WO-2025063899-A1 A DYNAMIC CROSSLINKER, COVALENT ADAPTABLE NETWORK COMPRISING POLYMER NETWORK CROSSLINKED BY SAID DYNAMIC CROSSLINKER AND RELATED METHODS THEREOF AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2025-03-27 WO disclosed
CN-116217911-B Wear-resistant polycarbonate 万华化学集团股份有限公司 2025-01-10 CN disclosed
CN-119080631-A Method for preparing N-aryl amide compound by catalyzing nitrite-mediated selenium 浙江工业大学 2024-12-06 CN disclosed
US-3932486-A GASTRIC SECRETION INHIBITORS, ANTISPASMODIC, ANTIASTHMATIC, HYPOTENSIVE THE UPJOHN COMPANY (US) 1976-01-13 US disclosed
US-3931281-A PROSTAGLANDINS THE UPJOHN COMPANY (US) 1976-01-06 US disclosed
US-3931285-A PROSTAGLANDINS THE UPJOHN COMPANY (US) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120302611-A1 PESTICIDAL COMPOSITIONS AND RELATED METHODS PRDX6, PRDX2, PRDX1 DEGS1 793/4885POLB 4219/4885KDM4E 777/4885
US-20210332001-A1 SYNTHESIS AND ANTI-TUMOR ACTIVITIES OF ACYL-PARA-AMINOPHENOL DERIVATIVES AADAC, FABP7, NPEPPS DEGS1 3593/4885POLB 1743/4885KDM4E 592/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.