Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAAT3 | P53816 | 2/20 | 0.42 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.42 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.42 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7620776 | 0.89 | HDAC3 (0.49) | PLAAT3PLAAT5PLAAT2PLAAT4LTB4R | |
| SCHEMBL7615412 | 0.89 | HDAC3 (0.49) | PLAAT3PLAAT5PLAAT2PLAAT4LTB4R | |
| SCHEMBL682183 | 0.89 | HDAC3 (0.49) | PLAAT3PLAAT5PLAAT2PLAAT4LTB4R | |
| SCHEMBL7616067 | 0.83 | OPRK1 (0.40) | PLAAT3PLAAT5PLAAT2PLAAT4LTB4R | |
| SCHEMBL9056155 | 0.83 | S1PR2 (0.46) | LTB4RHDAC1 | |
| SCHEMBL4661178 | 0.82 | HDAC3 (0.50) | PLAAT3PLAAT5PLAAT2PLAAT4LTB4R | |
| SCHEMBL8463990 | 0.81 | HDAC3 (0.42) | PLAAT3PLAAT5PLAAT2PLAAT4LTB4R | |
| SCHEMBL7613532 | 0.81 | S1PR2 (0.42) | PLAAT3PLAAT5PLAAT2PLAAT4LTB4R | |
| SCHEMBL7616376 | 0.81 | S1PR2 (0.42) | PLAAT3PLAAT5PLAAT2PLAAT4LTB4R | |
| SCHEMBL4662607 | 0.80 | ACACB (0.45) | PLAAT3PLAAT5PLAAT2PLAAT4LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790824-B1 | 2,2-DICHLOROALKANE CARBOXYLIC ACIDS, PROCESS FOR PREPARING THE SAME, MEDICAMENT CONTAINING THE SAME, AND USE THEREOF FOR TREATING INSULIN RESISTANCE | ROCHE DIAGNOSTICS GMBH (DE) | 2002-02-06 | — | — | EP | disclosed |
| US-5968982-A | TREATMENT OF DIABETES | ROCHE DIAGNOSTICS GMBH (DE) | 1999-10-19 | — | — | US | disclosed |