Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 3/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL405100 | 0.82 | TAAR1 (0.48) | RAB9ANPC1DAOTAAR1RNASEH1 | |
| SCHEMBL570036 | 0.71 | TAAR1 (0.69) | PDE10ARAB9ANPC1DAOTAAR1 | |
| SCHEMBL3679069 | 0.71 | TAAR1 (0.47) | PDE10ARAB9ANPC1DAOTAAR1 | |
| Hydrochloric Acid SCHEMBL1846181 | 0.69 | TAAR1 (0.67) | PDE10ARAB9ANPC1TAAR1MAOA | |
| Benzene SCHEMBL3440179 | 0.68 | ALDH1A1 (0.69) | TAAR1KCNH2MAOAMAOBALDH1A1 | |
| SCHEMBL9741303 | 0.68 | ALDH1A1 (0.69) | TAAR1KCNH2MAOAMAOBALDH1A1 | |
| SCHEMBL62125 | 0.68 | ALDH1A1 (0.69) | TAAR1KCNH2MAOAMAOBALDH1A1 | |
| SCHEMBL10704195 | 0.68 | RAB9A (0.46) | PDE10ARAB9ANPC1DAOTAAR1 | |
| SCHEMBL25403475 | 0.65 | ALDH1A1 (0.65) | TAAR1KCNH2MAOAMAOBALDH1A1 | |
| SCHEMBL11747668 | 0.65 | ALDH1A1 (0.65) | TAAR1KCNH2MAOAMAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1232166-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | Pharmasset Limited (US) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001034618-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | PHARMASSET LIMITED (US) | 2001-05-17 | — | — | WO | disclosed |