Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.48 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7623946 | 0.82 | PDE10A (0.46) | TAAR1DAOHRH3NPC1RAB9A | |
| SCHEMBL7616832 | 0.81 | MAPT (0.39) | TAAR1NR1H2DAONPC1RAB9A | |
| SCHEMBL7626665 | 0.81 | TAAR1 (0.37) | TAAR1GAADAOPKMLMNA | |
| SCHEMBL7621159 | 0.80 | DAO (0.42) | TAAR1DAOLMNA | |
| SCHEMBL7620401 | 0.79 | TAAR1 (0.44) | TAAR1DAO | |
| SCHEMBL7621725 | 0.77 | LTA4H (0.46) | POLBLMNACYP2D6 | |
| SCHEMBL14570954 | 0.69 | TAAR1 (0.50) | TAAR1CALM1GAANR1H2NR1H3 | |
| SCHEMBL7615355 | 0.69 | CALM1 (0.37) | CALM1DAOKMT2ATSHRMEN1 | |
| SCHEMBL795316 | 0.68 | NR1H2 (0.44) | TAAR1CALM1GAANR1H2NR1H3 | |
| SCHEMBL7385670 | 0.67 | GAA (0.44) | TAAR1CALM1GAANR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8361627-B2 | Anti-corrosion layer for aluminum and magnesium alloys | EADS DEUTSCHLAND GMBH (DE) | 2013-01-29 | — | — | US | disclosed |
| US-20120021232-A1 | ANTI-CORROSION LAYER FOR ALUMINUM AND MAGNESIUM ALLOYS | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2012-01-26 | — | — | US | disclosed |
| EP-1744751-A2 | METHODS FOR THE TREATMENT OF SYNUCLEINOPATHIES | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2007-01-24 | — | — | EP | disclosed |
| EP-1446113-A4 | COMPOUNDS AND METHODS FOR TREATING TRANSPLANT REJECTION | ATHEROGENICS INC (US) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005089502-A2 | METHODS FOR THE TREATMENT OF SYNUCLEINOPATHIES | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2005-09-29 | — | — | WO | disclosed |
| EP-1446113-A2 | COMPOUNDS AND METHODS FOR TREATING TRANSPLANT REJECTION | Atherogenics, Inc. (US) | 2004-08-18 | — | — | EP | disclosed |
| WO-2004024094-A2 | METHODS AND COMPOSITONS FOR THE USE OF D-MALIC ACID TO DECREASE SERUM TRIGLYCERIDE, CHOLESTEROL, AND LIPOPROTEIN LEVELS | SAMFORD UNIVERSITY (US) | 2004-03-25 | — | — | WO | disclosed |
| WO-2003039231-A2 | COMPOUNDS AND METHODS FOR TREATING TRANSPLANT REJECTION | ATHEROGENICS, INC. (US) | 2003-05-15 | — | — | WO | disclosed |
| EP-1232166-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | Pharmasset Limited (US) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001034618-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | PHARMASSET LIMITED (US) | 2001-05-17 | — | — | WO | disclosed |
| WO-1999051590-A1 | SUBSTITUTED INDOLINONES AS KINASE INHIBITORS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-10-14 | — | — | WO | disclosed |