Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28252591 | 0.84 | ALDH1A1 (0.69) | ALDH1A1HIF1AMAPK1MAPTKMT2A | |
| SCHEMBL85604 | 0.84 | ALDH1A1 (0.69) | ALDH1A1HIF1AMAPK1MAPTKMT2A | |
| SCHEMBL29379039 | 0.84 | ALDH1A1 (0.69) | ALDH1A1HIF1AMAPK1MAPTKMT2A | |
| Bicarbonate SCHEMBL28637012 | 0.82 | ALDH1A1 (0.58) | ALDH1A1HIF1AHTTTHRBGAA | |
| Hydrochloric Acid SCHEMBL30306150 | 0.82 | ALDH1A1 (0.67) | ALDH1A1HIF1AMAPK1MAPTKMT2A | |
| SCHEMBL27621933 | 0.79 | ALDH1A1 (0.58) | ALDH1A1HIF1AHTTTHRBGAA | |
| SCHEMBL4379631 | 0.79 | RECQL (0.54) | ALDH1A1HIF1AHTTTHRBL3MBTL1 | |
| SCHEMBL5505279 | 0.79 | CYP4F2 (0.54) | ALDH1A1HIF1AHTTTHRBGAA | |
| SCHEMBL1360146 | 0.76 | MAPT (0.56) | ALDH1A1HIF1AHTTTHRBGAA | |
| SCHEMBL2832 | 0.76 | ALDH1A1 (0.55) | ALDH1A1HIF1AHTTTHRBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144459-B1 | CROSS-LINKED HYALURONIC ACIDS AND MEDICAL USES THEREOF | AQUISITIO S P A (IT) | 2002-10-02 | — | — | EP | disclosed |
| EP-1144459-A2 | CROSS-LINKED HYALURONIC ACIDS AND MEDICAL USES THEREOF | Aquisitio S.p.A. (IT) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000027887-A2 | CROSS-LINKED HYALURONIC ACIDS AND MEDICAL USES THEREOF | AQUISITIO S.P.A. (IT) | 2000-05-18 | — | — | WO | disclosed |