SCHEMBL28252591

SCHEMBL28252591

O=[N+]([O-])c1ccc(F)c(F)c1.O=[N+]([O-])c1ccc(F)c(F)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.69
HIF1A Q16665 1/20 0.69
TSHR P16473 3/20 0.52
LMNA P02545 2/20 0.52
TDP1 Q9NUW8 4/20 0.50
KMT2A Q03164 2/20 0.50
HSD17B10 Q99714 1/20 0.50
PTPRC P08575 1/20 0.48
S100A4 P26447 1/20 0.48
CYP19A1 P11511 1/20 0.48
GPR35 Q9HC97 2/20 0.47
CYP3A4 P08684 1/20 0.47
TP53 P04637 1/20 0.47
HPGD P15428 1/20 0.47
MAPK1 P28482 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
HSP90AA1 P07900 1/20 0.47
MEN1 O00255 1/20 0.46
MAPT P10636 1/20 0.46
HSPB1 P04792 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29379039 1.00 ALDH1A1 (0.69) ALDH1A1HIF1ATSHRLMNATDP1
SCHEMBL85604 1.00 ALDH1A1 (0.69) ALDH1A1HIF1ATSHRLMNATDP1
Hydrochloric Acid SCHEMBL30306150 0.98 ALDH1A1 (0.67) ALDH1A1HIF1ATSHRLMNATDP1
SCHEMBL27621933 0.90 ALDH1A1 (0.58) ALDH1A1HIF1ATSHRLMNATDP1
Bicarbonate SCHEMBL28637012 0.90 ALDH1A1 (0.58) ALDH1A1HIF1ATSHRLMNATDP1
SCHEMBL4910527 0.84 ALDH1A1 (0.67) ALDH1A1HIF1ATSHRLMNATDP1
SCHEMBL7624344 0.84 ALDH1A1 (0.51) ALDH1A1HIF1ATSHRLMNATDP1
SCHEMBL27739457 0.84 TDP1 (0.73) ALDH1A1HIF1ATSHRLMNATDP1
SCHEMBL20380174 0.82 MAPT (0.58) ALDH1A1HIF1ALMNATDP1KMT2A
SCHEMBL35276 0.82 ALDH1A1 (1.00) ALDH1A1HIF1ATSHRLMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106397358-B A kind of method of the micro passage reaction synthesis fluoro- 4- of 3- (4- morpholinyl) aniline 黑龙江鑫创生物科技开发有限公司 2018-11-20 CN disclosed