Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7102887 | 0.91 | MMP13 (0.54) | MAPTMMP13SLC22A8POLBMAPK1 | |
| SCHEMBL7102983 | 0.91 | MMP13 (0.54) | MAPTMMP13SLC22A8POLBMAPK1 | |
| SCHEMBL6246256 | 0.87 | MAPT (0.58) | MAPTMMP13SLC22A8KDM4EHDAC1 | |
| SCHEMBL7101956 | 0.87 | MMP13 (0.54) | MAPTMMP13SLC22A8MAPK1L3MBTL1 | |
| SCHEMBL6517292 | 0.87 | MAPT (0.59) | MAPTMMP13SLC22A8MAPK1L3MBTL1 | |
| SCHEMBL7095851 | 0.85 | MMP13 (0.65) | MAPTMMP13SLC22A8MAPK1L3MBTL1 | |
| SCHEMBL6471030 | 0.85 | MMP13 (0.51) | MAPTMMP13POLBKDM4EHDAC1 | |
| SCHEMBL6532934 | 0.84 | PPARG (0.56) | MAPTMMP13SLC22A8MAPK1L3MBTL1 | |
| SCHEMBL7100567 | 0.84 | MMP13 (0.56) | MAPTMMP13SLC22A8MAPK1L3MBTL1 | |
| SCHEMBL6234634 | 0.83 | MMP13 (0.58) | MAPTMMP13POLBKDM4EHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020193377-A1 | Quinazolines as MMP-13 inhibitors | ANDRIANJARA CHARLES (FR) | 2002-12-19 | — | — | US | claimed |
| US-20020193377-A1 | Quinazolines as MMP-13 inhibitors | ANDRIANJARA CHARLES (FR) | 2002-12-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193377-A1 | Quinazolines as MMP-13 inhibitors | MMP13, MMP9, MMP3 | MAPT 4823/4885MMP13 1/4885SLC22A8 315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.