SCHEMBL7624565

SCHEMBL7624565

CCCCCOc1ccc(P(=O)(C(=O)c2c(Cl)cccc2Cl)C(=O)c2c(Cl)cccc2Cl)c(OCCCCC)c1

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GGPS1 O95749 2/20 0.45
SMPD1 P17405 3/20 0.44
PTPN11 Q06124 2/20 0.43
PLA2G4B P0C869 2/20 0.43
THRB P10828 2/20 0.42
THRA P10827 1/20 0.42
NR1H4 Q96RI1 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7627834 0.87 GGPS1 (0.46) GGPS1SMPD1PTPN11PLA2G4BTHRB
SCHEMBL29715644 0.87 GGPS1 (0.46) GGPS1SMPD1PTPN11PLA2G4BTHRB
SCHEMBL5144192 0.86 THRB (0.47) GGPS1SMPD1PTPN11PLA2G4BTHRB
SCHEMBL4710769 0.85 THRA (0.48) GGPS1SMPD1PTPN11PLA2G4BTHRB
SCHEMBL150337 0.82 ITGB1 (0.49) GGPS1SMPD1PTPN11PLA2G4BTHRB
SCHEMBL4624645 0.81 ITGB1 (0.48) GGPS1SMPD1PTPN11PLA2G4BTHRB
SCHEMBL29660598 0.81 ITGB1 (0.48) GGPS1SMPD1PTPN11PLA2G4BTHRB
SCHEMBL4625245 0.81 ITGB1 (0.48) GGPS1SMPD1PTPN11PLA2G4BTHRB
SCHEMBL5043176 0.80 ITGB1 (0.43) GGPS1SMPD1PTPN11PLA2G4BTHRB
SCHEMBL444479 0.80 ITGB1 (0.46) GGPS1PTPN11THRBTHRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6486228-B2 BIS-ACYLPHOSPHINE OXIDES AND ACYLPHOSPHINE OXIDES FOR CURING PHOTOPOLYMERIZABLE COMPOSITIONS WITHOUT YELLOWING; USE IN WHITE SURFACE COATINGS, AS NEGATIVE PHOTORESISTS, IN PRINTING PLATES CIBA SPECIALTY CHEMICALS CORPORATION 2002-11-26 US disclosed
US-20010036978-A1 Photoinitiator combinations IGM GROUP B.V. (NL) 2001-11-01 US disclosed
US-6251963-B1 ORGAOPHOSPHOROUS COMPOUND CONTAINING KETONE GROUP CIBA SPECIALTY CHEMICALS CORPORATION 2001-06-26 US disclosed