Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 6/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4710769 | 0.99 | THRA (0.48) | THRBTHRAGGPS1SMPD1PTPN11 | |
| SCHEMBL5043176 | 0.93 | ITGB1 (0.43) | THRBTHRAGGPS1SMPD1PTPN11 | |
| SCHEMBL29715644 | 0.87 | GGPS1 (0.46) | THRBTHRAGGPS1SMPD1PTPN11 | |
| SCHEMBL7627834 | 0.87 | GGPS1 (0.46) | THRBTHRAGGPS1SMPD1PTPN11 | |
| SCHEMBL7624565 | 0.86 | GGPS1 (0.45) | THRBTHRAGGPS1SMPD1PTPN11 | |
| SCHEMBL8536848 | 0.82 | L3MBTL1 (0.44) | — | |
| SCHEMBL150337 | 0.82 | ITGB1 (0.49) | THRBTHRAGGPS1SMPD1PTPN11 | |
| SCHEMBL4624645 | 0.81 | ITGB1 (0.48) | THRBTHRAGGPS1SMPD1PTPN11 | |
| SCHEMBL4625245 | 0.81 | ITGB1 (0.48) | THRBTHRAGGPS1SMPD1PTPN11 | |
| SCHEMBL4711652 | 0.81 | MAPT (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7214830-B2 | Process for the preparation of acylphosphines, acyl oxides and acyl sulfides | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-05-08 | — | — | US | disclosed |
| US-7094931-B2 | Process for the preparation of acylphosphines, acyl oxides and acyl sulfides | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2006-08-22 | — | — | US | disclosed |
| EP-1135399-B2 | PROCESS FOR PREPARING ACYLPHOSPHINES AND DERIVATIVES | CIBA SC HOLDING AG (CH) | 2006-08-09 | — | — | EP | disclosed |
| US-20060128959-A1 | Process for the preparation of acylphosphines, acyl oxides and acyl sulfides | IGM GROUP B.V. (NL) | 2006-06-15 | — | — | US | disclosed |
| US-6888031-B1 | Process for the preparation of acylphosphines, acyl oxides and acyl sulfides | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2005-05-03 | — | — | US | disclosed |
| US-20040248855-A1 | Process for the preparation of acylphosphines, acyl oxides and acyl sulfides | IGM GROUP B.V. (NL) | 2004-12-09 | — | — | US | disclosed |
| US-6486228-B2 | BIS-ACYLPHOSPHINE OXIDES AND ACYLPHOSPHINE OXIDES FOR CURING PHOTOPOLYMERIZABLE COMPOSITIONS WITHOUT YELLOWING; USE IN WHITE SURFACE COATINGS, AS NEGATIVE PHOTORESISTS, IN PRINTING PLATES | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-11-26 | — | — | US | disclosed |
| EP-1135399-B1 | PROCESS FOR PREPARING ACYLPHOSPHINES AND DERIVATIVES | CIBA SC HOLDING AG (CH) | 2002-08-07 | — | — | EP | disclosed |
| US-20010036978-A1 | Photoinitiator combinations | IGM GROUP B.V. (NL) | 2001-11-01 | — | — | US | disclosed |
| EP-1135399-A1 | PROCESS FOR PREPARING ACYLPHOSPHINES AND DERIVATIVES | Ciba SC Holding AG (CH) | 2001-09-26 | — | — | EP | disclosed |
| US-6251963-B1 | ORGAOPHOSPHOROUS COMPOUND CONTAINING KETONE GROUP | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-06-26 | — | — | US | disclosed |
| WO-2000032612-A1 | PROCESS FOR PREPARING ACYLPHOSPHINES AND DERIVATIVES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-06-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128959-A1 | Process for the preparation of acylphosphines, acyl oxides and acyl sulfides | AGPS, PHOSPHO1, AGPAT2 | THRB 3900/4885THRA 3429/4885GGPS1 387/4885 |
| US-20040248855-A1 | Process for the preparation of acylphosphines, acyl oxides and acyl sulfides | AGPS, PHOSPHO1, AGPAT2 | THRB 3871/4885THRA 3189/4885GGPS1 339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.