Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | NNMT | P40261 | 2/20 | 0.32 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.31 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.30 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7612236 | 0.66 | HTT (0.41) | SMN1; SMN2KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL21597733 | 0.61 | SMN1; SMN2 (0.34) | SMN1; SMN2HIF1AKDM4EHPGDHSD17B10 | |
| SCHEMBL7644422 | 0.60 | NNMT (0.32) | NNMT | |
| SCHEMBL28993058 | 0.60 | — | — | |
| SCHEMBL29795195 | 0.60 | NNMT (0.54) | SMN1; SMN2KDM4EHPGDHSD17B10NNMT | |
| SCHEMBL353814 | 0.60 | NNMT (0.54) | SMN1; SMN2KDM4EHPGDHSD17B10NNMT | |
| SCHEMBL15279084 | 0.59 | LOXL2 (0.39) | SMN1; SMN2HIF1A | |
| SCHEMBL24760036 | 0.58 | — | — | |
| SCHEMBL21737415 | 0.58 | — | — | |
| SCHEMBL9953840 | 0.57 | SMN1; SMN2 (0.37) | SMN1; SMN2HIF1ANNMTTSHRMKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002074267-A1 | NOVEL DYEING COMPOSITIONS FOR THE DYEING OF KERATIN FIBRES COMPRISING 6-MEMBERED HETEROCYCLIC HYDRAZONE COMPOUNDS AS AN OXIDATION BASE | L'OREAL (FR) | 2002-09-26 | — | — | WO | disclosed |