SCHEMBL7624876

SCHEMBL7624876

[CH2]COC[C](OOC(=O)c1cccc(-c2ccccc2)c1)OOC(=O)c1cccc(-c2ccccc2)c1

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KMO O15229 1/20 0.45
F2 P00734 1/20 0.43
LMNA P02545 1/20 0.43
MAPT P10636 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
ERCC5 P28715 1/20 0.42
FEN1 P39748 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7628767 0.93 KMO (0.42) KMOF2LMNAMAPTTDP1
SCHEMBL7624034 0.87 KDM4E (0.49) F2LMNAMAPTERCC5FEN1
SCHEMBL7627824 0.87 LMNA (0.59) F2LMNAMAPTTDP1NPC1
SCHEMBL7634500 0.85 KMO (0.50) KMOF2LMNAMAPTTDP1
SCHEMBL7624291 0.84 KMO (0.49) KMOF2LMNAMAPTTDP1
SCHEMBL7631027 0.82 NPC1 (0.47) TDP1HDAC8NPC1RAB9A
SCHEMBL7634180 0.82 KMO (0.46) KMOF2LMNAMAPTTDP1
SCHEMBL7627522 0.81 KMO (0.51) KMOF2LMNAMAPTTDP1
SCHEMBL7633964 0.81 KDM4E (0.46) F2LMNAMAPTERCC5FEN1
SCHEMBL7627931 0.81 KMO (0.45) KMOF2LMNAMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1233014-A1 ASYMMETRIC ORGANIC PEROXIDE, CROSSLINKING AGENT COMPRISING THE SAME, AND METHOD OF CROSSLINKING WITH THE SAME NOF CORPORATION (JP) 2002-08-21 EP disclosed