SCHEMBL7633964

SCHEMBL7633964

[CH2]COCCOC[C](OOC(=O)c1ccc(-c2ccccc2)cc1)OOC(=O)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.46
LMNA P02545 3/20 0.43
F2 P00734 1/20 0.43
PDCD1 Q15116 1/20 0.41
CD274 Q9NZQ7 1/20 0.41
SMN1; SMN2 Q16637 6/20 0.40
MAPT P10636 4/20 0.40
SLC1A5 Q15758 1/20 0.40
ALDH1A1 P00352 1/20 0.39
NPY1R P25929 1/20 0.39
NPY2R P49146 1/20 0.39
HDAC1 Q13547 1/20 0.37
HDAC2 Q92769 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
PTPN1 P18031 1/20 0.37
GSK3B P49841 1/20 0.37
RAB9A P51151 2/20 0.36
FFAR1 O14842 1/20 0.36
CYP1A2 P05177 1/20 0.36
HIF1A Q16665 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7624034 0.93 KDM4E (0.49) KDM4ELMNAF2PDCD1CD274
SCHEMBL7627403 0.91 LMNA (0.53) KDM4ELMNAF2SMN1; SMN2MAPT
SCHEMBL7628767 0.88 KMO (0.42) LMNAF2MAPTRAB9ANPC1
SCHEMBL7627824 0.84 LMNA (0.59) KDM4ELMNAF2SMN1; SMN2MAPT
SCHEMBL7625463 0.83 TDP1 (0.42) LMNAF2SMN1; SMN2MAPTALDH1A1
SCHEMBL7627324 0.82 ALDH1A1 (0.41) KDM4ELMNAF2SMN1; SMN2MAPT
SCHEMBL7633664 0.81 SCN1A (0.43) SMN1; SMN2ALDH1A1
SCHEMBL7624876 0.81 KMO (0.45) LMNAF2MAPTRAB9ANPC1
SCHEMBL7633259 0.81 CA1 (0.46) KDM4ELMNASMN1; SMN2MAPTALDH1A1
SCHEMBL7636196 0.81 LMNA (0.53) KDM4ELMNAF2PDCD1CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1233014-A1 ASYMMETRIC ORGANIC PEROXIDE, CROSSLINKING AGENT COMPRISING THE SAME, AND METHOD OF CROSSLINKING WITH THE SAME NOF CORPORATION (JP) 2002-08-21 EP disclosed