⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3071835 | 0.78 | MMP1 (0.38) | — | |
| SCHEMBL739862 | 0.73 | ALDH1A1 (0.43) | — | |
| SCHEMBL3071224 | 0.69 | LAP3 (0.35) | — | |
| SCHEMBL440980 | 0.68 | — | — | |
| SCHEMBL240710 | 0.68 | — | — | |
| SCHEMBL3062832 | 0.67 | CA12 (0.31) | — | |
| SCHEMBL11995816 | 0.65 | — | — | |
| SCHEMBL17626543 | 0.65 | LAP3 (0.47) | — | |
| Hydrochloric Acid SCHEMBL10904960 | 0.65 | — | — | |
| SCHEMBL17626398 | 0.65 | LAP3 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138154-B2 | Biglycan and related therapeutics and methods of use | BROWN UNIVERSITY RESEARCH FOUNDATION (US) | 2012-03-20 | — | — | US | disclosed |
| US-20100130405-A1 | BIGLYCAN AND RELATED THERAPEUTICS AND METHODS OF USE | BROWN TECHNOLOGY PARTNERSHIPS (US) | 2010-05-27 | — | — | US | disclosed |