SCHEMBL7625397

SCHEMBL7625397

COc1ccccc1C(=O)OO[C]1CC(C)CCC1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.42
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
HPGD P15428 3/20 0.41
MAPT P10636 2/20 0.41
XBP1 P17861 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
TAS1R3 Q7RTX0 1/20 0.41
TAS1R1 Q7RTX1 1/20 0.41
TAS1R2 Q8TE23 1/20 0.41
ALDH1A1 P00352 2/20 0.40
PIN1 Q13526 1/20 0.40
GAA P10253 1/20 0.39
CHRM2 P08172 1/20 0.39
CHRM4 P08173 1/20 0.39
CHRM5 P08912 1/20 0.39
CHRM1 P11229 1/20 0.39
CHRM3 P20309 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7625936 0.85 HPGD (0.43) ATMNPC1RAB9AHPGDMAPT
SCHEMBL7630185 0.84 NPC1 (0.37) NPC1RAB9AMAPTNPSR1MEN1
SCHEMBL7629946 0.82 ATM (0.47) ATMHPGDMAPTXBP1NPSR1
SCHEMBL7625231 0.81 PIN1 (0.41) ATMNPC1RAB9AHPGDMAPT
SCHEMBL7634382 0.79 ATM (0.44) ATMNPC1RAB9AHPGDMAPT
SCHEMBL7625567 0.77 ATM (0.47) ATMNPC1RAB9AHPGDMAPT
SCHEMBL7636276 0.77 PIN1 (0.45) ATMNPC1RAB9AHPGDMAPT
SCHEMBL7625790 0.77 TAS1R3 (0.38) NPC1RAB9AMAPTMEN1KMT2A
SCHEMBL7628114 0.76 ATM (0.46) ATMHPGDMAPTXBP1NPSR1
SCHEMBL7626136 0.76 KMT2A (0.39) MEN1KMT2ATAS1R3TAS1R1TAS1R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1233014-A1 ASYMMETRIC ORGANIC PEROXIDE, CROSSLINKING AGENT COMPRISING THE SAME, AND METHOD OF CROSSLINKING WITH THE SAME NOF CORPORATION (JP) 2002-08-21 EP disclosed