SCHEMBL7625567

SCHEMBL7625567

COc1ccccc1C(=O)OO[C]1C(C)CCCC1C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.47
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
NPSR1 Q6W5P4 2/20 0.44
HPGD P15428 2/20 0.44
XBP1 P17861 1/20 0.44
MAPT P10636 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.43
NPC1 O15118 2/20 0.43
HTT P42858 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
ALDH1A1 P00352 1/20 0.43
STAT3 P40763 1/20 0.42
PIN1 Q13526 1/20 0.42
RAB9A P51151 2/20 0.42
GAA P10253 1/20 0.42
CHRM2 P08172 1/20 0.41
CHRM4 P08173 1/20 0.41
CHRM5 P08912 1/20 0.41
CHRM1 P11229 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7625741 0.83 NPC1 (0.42) MEN1KMT2ANPSR1MAPTNPC1
SCHEMBL7629946 0.83 ATM (0.47) ATMMEN1KMT2ANPSR1HPGD
SCHEMBL7634382 0.79 ATM (0.44) ATMMEN1KMT2ANPSR1HPGD
SCHEMBL7625957 0.78 LMNA (0.50) ATMMEN1KMT2ATDP1ALDH1A1
SCHEMBL7636276 0.78 PIN1 (0.45) ATMMEN1KMT2ANPSR1HPGD
SCHEMBL7625397 0.77 ATM (0.42) ATMMEN1KMT2ANPSR1HPGD
SCHEMBL7630313 0.77 ESR1 (0.51) ATMMEN1KMT2ANPSR1HPGD
SCHEMBL7634349 0.77 MAPT (0.51) ATMMEN1KMT2ANPSR1HPGD
SCHEMBL48968 0.77 HPGD (0.59) KMT2ANPSR1HPGDXBP1MAPT
SCHEMBL7628114 0.76 ATM (0.46) ATMMEN1KMT2ANPSR1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1233014-A1 ASYMMETRIC ORGANIC PEROXIDE, CROSSLINKING AGENT COMPRISING THE SAME, AND METHOD OF CROSSLINKING WITH THE SAME NOF CORPORATION (JP) 2002-08-21 EP disclosed