Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.34 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7627840 | 0.82 | NPC1 (0.40) | ALDH1A1CYP2C19HPGDSMN1; SMN2NPC1 | |
| SCHEMBL7633376 | 0.81 | NPC1 (0.38) | ALDH1A1CYP2C19HPGDSMN1; SMN2NPC1 | |
| SCHEMBL5854820 | 0.81 | NPC1 (0.39) | ALDH1A1CYP2C19HPGDSMN1; SMN2NPC1 | |
| SCHEMBL5853858 | 0.81 | NPC1 (0.39) | ALDH1A1CYP2C19HPGDSMN1; SMN2NPC1 | |
| SCHEMBL5852745 | 0.80 | NPC1 (0.40) | ALDH1A1CYP2C19HPGDSMN1; SMN2NPC1 | |
| SCHEMBL5853185 | 0.75 | HPGD (0.36) | ALDH1A1CYP2C19HPGDSMN1; SMN2NPC1 | |
| SCHEMBL5852732 | 0.75 | HPGD (0.36) | ALDH1A1CYP2C19HPGDSMN1; SMN2NPC1 | |
| SCHEMBL5853957 | 0.74 | NPC1 (0.36) | ALDH1A1CYP2C19HPGDNPC1RAB9A | |
| SCHEMBL7633227 | 0.72 | ALDH1A1 (0.39) | ALDH1A1CYP2C19HPGDSMN1; SMN2MEN1 | |
| SCHEMBL7636915 | 0.72 | ALDH1A1 (0.39) | ALDH1A1CYP2C19HPGDSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0849288-B1 | Catalyst for polymerization of an olefin, and method for producing an olefin polymer | TOSOH CORP (JP) | 2002-11-27 | — | — | EP | disclosed |
| US-5906955-A | Catalyst for polymerization of an olefin, and method for producing an olefin polymer | TOSOH CORPORATION (JP) | 1999-05-25 | — | — | US | disclosed |
| EP-0849288-A1 | Catalyst for polymerization of an olefin, and method for producing an olefin polymer | TOSOH CORPORATION (JP) | 1998-06-24 | — | — | EP | disclosed |