SCHEMBL7633227

SCHEMBL7633227

C[SiH](C)[Zr](Cc1ccccc1)(Cc1ccccc1)(NC(=O)C1CCCCC1)c1cccc2c1Cc1ccccc1-2

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.39
CYP2C19 P33261 2/20 0.39
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
ALOX12 P18054 3/20 0.36
HPGD P15428 2/20 0.36
USP2 O75604 1/20 0.36
KDM4E B2RXH2 3/20 0.36
GAA P10253 1/20 0.36
HTT P42858 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
LMNA P02545 2/20 0.35
RECQL P46063 1/20 0.35
CTSV O60911 1/20 0.33
CTSL P07711 1/20 0.33
CTSS P25774 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7628547 0.83 NPC1 (0.40) ALDH1A1CYP2C19MEN1KMT2ANPC1
SCHEMBL7626477 0.82 NPC1 (0.38) ALDH1A1CYP2C19NPC1RAB9AHPGD
SCHEMBL5854780 0.82 NPC1 (0.39) ALDH1A1CYP2C19KMT2ANPC1RAB9A
SCHEMBL5855675 0.82 NPC1 (0.39) ALDH1A1CYP2C19KMT2ANPC1RAB9A
SCHEMBL5852838 0.81 NPC1 (0.40) ALDH1A1CYP2C19NPC1RAB9AHPGD
SCHEMBL5854870 0.76 HPGD (0.39) ALDH1A1CYP2C19NPC1RAB9AHPGD
SCHEMBL5854766 0.76 HPGD (0.39) ALDH1A1CYP2C19NPC1RAB9AHPGD
SCHEMBL5853516 0.75 HPGD (0.37) ALDH1A1CYP2C19NPC1RAB9AHPGD
SCHEMBL7636915 0.72 ALDH1A1 (0.39) ALDH1A1CYP2C19MEN1KMT2ANPC1
SCHEMBL7626262 0.72 ALDH1A1 (0.39) ALDH1A1CYP2C19MEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0849288-B1 Catalyst for polymerization of an olefin, and method for producing an olefin polymer TOSOH CORP (JP) 2002-11-27 EP disclosed
US-5906955-A Catalyst for polymerization of an olefin, and method for producing an olefin polymer TOSOH CORPORATION (JP) 1999-05-25 US disclosed
EP-0849288-A1 Catalyst for polymerization of an olefin, and method for producing an olefin polymer TOSOH CORPORATION (JP) 1998-06-24 EP disclosed