Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | CCKAR | P32238 | 1/20 | 0.32 |
| ▸ | CCKBR | P32239 | 1/20 | 0.32 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.32 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5854820 | 1.00 | NPC1 (0.39) | NPC1RAB9ACYP2C19ALDH1A1KDM4E | |
| SCHEMBL5852745 | 0.99 | NPC1 (0.40) | NPC1RAB9ACYP2C19ALDH1A1KDM4E | |
| SCHEMBL5852732 | 0.88 | HPGD (0.36) | NPC1RAB9ACYP2C19ALDH1A1KDM4E | |
| SCHEMBL5853185 | 0.88 | HPGD (0.36) | NPC1RAB9ACYP2C19ALDH1A1KDM4E | |
| SCHEMBL5853957 | 0.86 | NPC1 (0.36) | NPC1RAB9ACYP2C19ALDH1A1KDM4E | |
| SCHEMBL7627840 | 0.86 | NPC1 (0.40) | NPC1RAB9ACYP2C19ALDH1A1KDM4E | |
| SCHEMBL7633376 | 0.85 | NPC1 (0.38) | NPC1RAB9ACYP2C19ALDH1A1KDM4E | |
| SCHEMBL5853400 | 0.83 | RAB9A (0.51) | NPC1RAB9AALDH1A1KDM4EHTR7 | |
| SCHEMBL7626262 | 0.81 | ALDH1A1 (0.39) | NPC1RAB9ACYP2C19ALDH1A1KDM4E | |
| SCHEMBL5855486 | 0.80 | NPC1 (0.42) | NPC1RAB9AHTR7HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7037989-B2 | Copolymers of ethylene and/or α-olefins and vicinally disubstituted olefins | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-05-02 | — | — | US | disclosed |
| WO-2004106394-A1 | COPOLYMERS OF ETHYLENE AND/OR α-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-12-09 | — | — | WO | disclosed |
| US-20040242814-A1 | COPOLYMERS OF ETHYLENE AND/OR ALPHA-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-12-02 | — | — | US | disclosed |