Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CTSD | P07339 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1639354 | 0.89 | CA1 (0.60) | ALDH1A1MAPTMAPK1L3MBTL1GAA | |
| SCHEMBL6889991 | 0.86 | MAPT (0.59) | ALDH1A1MAPTTDP1MAPK1L3MBTL1 | |
| SCHEMBL17536014 | 0.86 | MAPT (0.50) | ALDH1A1MAPTTDP1MAPK1L3MBTL1 | |
| SCHEMBL29744518 | 0.81 | MAPT (0.72) | ALDH1A1MAPTTDP1MAPK1L3MBTL1 | |
| SCHEMBL2095055 | 0.81 | MAPT (0.72) | ALDH1A1MAPTTDP1MAPK1L3MBTL1 | |
| SCHEMBL28860257 | 0.81 | AHR (0.63) | ALDH1A1MAPTGAAHTTNPC1 | |
| SCHEMBL11506266 | 0.80 | MEN1 (0.53) | ALDH1A1MAPTMAPK1L3MBTL1GAA | |
| SCHEMBL22169131 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MAPTCTSDTDP1MAPK1 | |
| Hydrochloric Acid SCHEMBL7128944 | 0.79 | MAPT (0.70) | ALDH1A1MAPTTDP1MAPK1L3MBTL1 | |
| SCHEMBL22169140 | 0.79 | GAA (0.51) | ALDH1A1MAPTCTSDTDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10703746-B2 | Mutant IDH1 inhibitors useful for treating cancer | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2020-07-07 | — | — | US | disclosed |
| EP-1194409-A1 | PYRAZOLIDINOL COMPOUNDS | A-Viral AS (NO) | 2002-04-10 | — | — | EP | disclosed |
| WO-2001000585-A1 | PYRAZOLIDINOL COMPOUNDS | A-VIRAL AS (NO) | 2001-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10703746-B2 | Mutant IDH1 inhibitors useful for treating cancer | IDH1, IDH3B, IDH3A | ALDH1A1 417/4885MAPT 4568/4885CTSD 3836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.