Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MMP14 | P50281 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7626397 | 0.86 | ALDH1A1 (0.50) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL17536014 | 0.85 | MAPT (0.50) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL9770549 | 0.85 | MAPT (0.46) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL11650380 | 0.85 | KCNH2 (0.52) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL1639354 | 0.84 | CA1 (0.60) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL30741238 | 0.83 | MAPT (0.71) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL17201829 | 0.83 | MAPT (0.71) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL11770932 | 0.80 | POLB (0.50) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL11410117 | 0.80 | RAB9A (0.51) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL4909838 | 0.80 | CYP1A2 (0.62) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040143138-A1 | Process for the preparation of nitrodiphenylamines | LANXESS DEUTSCHLAND GMBH (DE) | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040143138-A1 | Process for the preparation of nitrodiphenylamines | HNMT, PNMT, NNMT | MAPT 1465/4885RAB9A 2532/4885SMN1; SMN2 3345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.