Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 16/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | CCKAR | P32238 | 1/20 | 0.52 |
| ▸ | GABRP | O00591 | 1/20 | 0.52 |
| ▸ | GABRD | O14764 | 1/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.52 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.52 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.52 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.52 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.52 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.52 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.52 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.52 |
| ▸ | GABRE | P78334 | 1/20 | 0.52 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.52 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.52 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.52 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.52 |
| ▸ | NOTCH1 | P46531 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8863378 | 1.00 | CCKBR (0.55) | CCKBRKCNH2CCKARGABRPGABRD | |
| SCHEMBL9867211 | 0.88 | CCKBR (0.56) | CCKBRCCKARGABRPGABRDGABRA1 | |
| SCHEMBL9867739 | 0.86 | CCKBR (0.58) | CCKBRKCNH2CCKARGABRPGABRD | |
| SCHEMBL7312531 | 0.85 | CCKBR (0.40) | CCKBRKCNH2CCKARGABRPGABRD | |
| SCHEMBL10520112 | 0.84 | CCKBR (0.59) | CCKBRCCKARGABRPGABRDGABRA1 | |
| SCHEMBL7308632 | 0.84 | CCKBR (0.41) | CCKBRKCNH2CCKARNOTCH1NOTCH3 | |
| SCHEMBL9273794 | 0.84 | CCKBR (0.48) | CCKBRKCNH2CCKARGABRPGABRD | |
| SCHEMBL9368599 | 0.81 | CCKBR (0.57) | CCKBRKCNH2 | |
| SCHEMBL9260497 | 0.81 | CCKBR (0.46) | CCKBRKCNH2CCKARGABRPGABRD | |
| SCHEMBL7827288 | 0.81 | CCKBR (0.58) | CCKBRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023072-B1 | ANALGESIC COMPOSITIONS COMPRISING A CHOLECYSTOKININ AND AN OPIOID | PANOS THERAPEUTICS LTD (GB) | 2002-12-11 | — | — | EP | disclosed |