Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 16/20 | 0.56 |
| ▸ | CCKAR | P32238 | 1/20 | 0.50 |
| ▸ | GABRP | O00591 | 1/20 | 0.49 |
| ▸ | GABRD | O14764 | 1/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.49 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.49 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.49 |
| ▸ | GABRE | P78334 | 1/20 | 0.49 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.49 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.49 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.49 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.49 |
| ▸ | NOTCH1 | P46531 | 1/20 | 0.46 |
| ▸ | NOTCH3 | Q9UM47 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865708 | 0.89 | CCKBR (0.57) | CCKBRCCKAR | |
| SCHEMBL7626581 | 0.88 | CCKBR (0.55) | CCKBRCCKARGABRPGABRDGABRA1 | |
| SCHEMBL8863378 | 0.88 | CCKBR (0.55) | CCKBRCCKARGABRPGABRDGABRA1 | |
| SCHEMBL9867739 | 0.84 | CCKBR (0.58) | CCKBRCCKARGABRPGABRDGABRA1 | |
| SCHEMBL10520112 | 0.82 | CCKBR (0.59) | CCKBRCCKARGABRPGABRDGABRA1 | |
| SCHEMBL7308632 | 0.81 | CCKBR (0.41) | CCKBRCCKARNOTCH1NOTCH3 | |
| SCHEMBL9260497 | 0.81 | CCKBR (0.46) | CCKBRCCKARGABRPGABRDGABRA1 | |
| SCHEMBL9273794 | 0.80 | CCKBR (0.48) | CCKBRCCKARGABRPGABRDGABRA1 | |
| SCHEMBL7312531 | 0.79 | CCKBR (0.40) | CCKBRCCKARGABRPGABRDGABRA1 | |
| SCHEMBL10683374 | 0.75 | CCKBR (0.56) | CCKBRCCKARGABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5004741-A | Cholecystokinin(CCK); Treating Disorders Of The Gastrointestinal Tract, Central Nervous System And Of The Appetite Of Animals | MERCK & CO., INC. (US) | 1991-04-02 | — | — | US | disclosed |