Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 18/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4883355 | 0.84 | CTSA (0.51) | CTSA | |
| SCHEMBL27603568 | 0.84 | CTSA (0.51) | CTSA | |
| SCHEMBL646089 | 0.79 | AAK1 (0.44) | CTSA | |
| SCHEMBL739456 | 0.77 | SUCNR1 (0.49) | — | |
| SCHEMBL739452 | 0.77 | SUCNR1 (0.49) | — | |
| SCHEMBL19744371 | 0.75 | CTSA (0.55) | CTSA | |
| SCHEMBL31757758 | 0.75 | CTSA (0.55) | CTSA | |
| SCHEMBL19744367 | 0.75 | CTSA (0.55) | CTSA | |
| SCHEMBL31757886 | 0.75 | CTSS (0.44) | CTSA | |
| SCHEMBL13802935 | 0.75 | AAK1 (0.41) | CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138168-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-20 | — | — | US | disclosed |
| US-8138168-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-20 | — | — | US | disclosed |