Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 5/20 | 0.71 |
| ▸ | ECE1 | P42892 | 2/20 | 0.56 |
| ▸ | HPGDS | O60760 | 2/20 | 0.55 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.54 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.54 |
| ▸ | ITGAL | P20701 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | F10 | P00742 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14527560 | 0.85 | GHSR (0.73) | GHSRECE1ITGB2ICAM1ITGAL | |
| SCHEMBL7251039 | 0.85 | GHSR (0.70) | GHSRMEN1KMT2A | |
| SCHEMBL19088182 | 0.83 | KISS1R (0.65) | — | |
| SCHEMBL19088151 | 0.83 | KISS1R (0.65) | — | |
| SCHEMBL19088149 | 0.83 | KISS1R (0.65) | — | |
| SCHEMBL19088147 | 0.83 | KISS1R (0.65) | — | |
| SCHEMBL19088204 | 0.83 | KISS1R (0.65) | — | |
| SCHEMBL19088212 | 0.83 | KISS1R (0.65) | — | |
| SCHEMBL19088152 | 0.83 | KISS1R (0.65) | — | |
| SCHEMBL19088153 | 0.83 | KISS1R (0.65) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138218-B2 | Growth hormone secretagogues | IPSEN PHARMA S.A.S. (FR) | 2012-03-20 | — | — | US | disclosed |
| US-20090131478-A1 | Growth Hormone Secretagogues | IPSEN PHARMA S.A.S. (FR) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131478-A1 | Growth Hormone Secretagogues | GHSR, GHRHR, GHITM | GHSR 1/4885ECE1 1276/4885HPGDS 335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.