Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.33 |
| ▸ | CFD | P00746 | 1/20 | 0.33 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1930853 | 0.76 | EGFR (0.53) | EGFRTDP1CA12CA1CA2 | |
| SCHEMBL1930556 | 0.73 | SMN1; SMN2 (0.46) | EGFRSMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL8668410 | 0.70 | EGFR (0.40) | EGFRCA12CA1CA2CA9 | |
| SCHEMBL5692310 | 0.70 | ALDH1A1 (0.44) | CA12CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL18055616 | 0.68 | TDP1 (0.50) | TDP1KEAP1NFE2L2CA1CA2 | |
| SCHEMBL13611310 | 0.68 | FFAR1 (0.59) | CA2AKR1B1SMN1; SMN2RAB9AMEN1 | |
| SCHEMBL809030 | 0.67 | ALDH1A1 (0.60) | SMN1; SMN2RAB9AMEN1NPC1KMT2A | |
| Hydrochloric Acid SCHEMBL11060114 | 0.67 | ALDH1A1 (0.60) | SMN1; SMN2RAB9AMEN1NPC1KMT2A | |
| SCHEMBL340537 | 0.67 | AKR1C3 (0.55) | CA12CA1CA2CA9CA4 | |
| SCHEMBL851008 | 0.66 | ERCC1 (0.60) | EGFRTDP1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458869-B1 | ETCHANT/PRIMER COMPOSITION, AN ETCHANT/PRIMER/ADHESIVE MONOMER COMPOSITION, KITS USING THE SAME AND METHODS USING THE SAME FOR IMPROVED BONDING TO DENTAL STRUCTURES. THE ETCHANT/PRIMER COMPOSITION COMPRISES A COMPOUND HAVING THE | NATIONAL INSTITUTE OF STANDARDS OF TECHNOLOGY | 2002-10-01 | — | — | US | disclosed |
| EP-0741557-B1 | A METHOD AND COMPOSITION FOR PROMOTING IMPROVED ADHESION TO SUBSTRATES | US COMMERCE (US) | 1999-07-07 | — | — | EP | disclosed |
| US-5756560-A | Method and composition for promoting improved adhesion to substrates | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE COMMERCE (US) | 1998-05-26 | — | — | US | disclosed |
| US-5690840-A | Method and composition for promoting improved adhesion to substrates | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF COMMERCE (US) | 1997-11-25 | — | — | US | disclosed |
| US-5498643-A | Method and composition for promoting improved adhesion to substrates | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF COMMERCE (US) | 1996-03-12 | — | — | US | disclosed |