SCHEMBL851008

SCHEMBL851008

O=C(O)CNc1ccc(O)c(O)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERCC1 P07992 4/20 0.60
ERCC4 Q92889 4/20 0.60
ARG1 P05089 1/20 0.53
MAPT P10636 3/20 0.47
KDM4E B2RXH2 2/20 0.47
POLB P06746 2/20 0.47
GAA P10253 2/20 0.47
RGS12 O14924 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
LMNA P02545 1/20 0.47
HPGD P15428 1/20 0.47
TSHR P16473 1/20 0.47
NFKB1 P19838 1/20 0.47
APEX1 P27695 1/20 0.47
THPO P40225 1/20 0.47
BLM P54132 1/20 0.47
GNAI1 P63096 1/20 0.47
PMP22 Q01453 1/20 0.47
HIF1A Q16665 1/20 0.47
HSD17B10 Q99714 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL9710740 0.98 ERCC1 (0.58) ERCC1ERCC4ARG1MAPTKDM4E
SCHEMBL1930853 0.83 EGFR (0.53) ERCC1ERCC4MAPTKDM4EPOLB
SCHEMBL156253 0.83 ALDH1A1 (0.60) MAPTKDM4ERGS12TDP1HPGD
SCHEMBL11532312 0.83 HSD17B14 (0.50) ERCC1ERCC4MAPTKDM4ERGS12
SCHEMBL15933411 0.83 ALDH1A1 (0.53) ERCC1ERCC4MAPTPOLBGAA
SCHEMBL4761809 0.83 ALDH1A1 (0.44) ERCC1ERCC4MAPTPOLBGAA
SCHEMBL11532507 0.83 THRA (0.46) ERCC1ERCC4MAPTRGS12TDP1
SCHEMBL4312066 0.83 THRA (0.52) ERCC1ERCC4MAPTPOLBGAA
SCHEMBL155359 0.83 KMT2A (0.53) ERCC1ERCC4MAPTKDM4EPOLB
SCHEMBL6906254 0.82 ERCC1 (0.54) ERCC1ERCC4ARG1MAPTRGS12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119523843-A Skin care sun protection emulsion and preparation method and application thereof 广州芊植本草化妆品有限公司 2025-02-28 CN claimed
CN-115094423-B Inorganic membrane removing liquid suitable for aluminum substrate circuit board and application thereof 深圳市板明科技股份有限公司 2022-11-08 CN claimed
CN-115094423-A Inorganic film removing liquid suitable for aluminum substrate circuit board and application thereof 深圳市板明科技股份有限公司 2022-09-23 CN claimed
US-6824786-B2 TOPICAL APPLYING COSMETIC YU RUEY J (US) 2004-11-30 US claimed
EP-1455734-A1 COMPOSITIONS COMPRISING PHENYL-GLYCINE DERIVATIVES Yu, Ruey J., Dr. (US) 2004-09-15 EP claimed
US-20030108496-A1 Compositions comprising phenyl-glycine derivatives YU RUEY J (US) 2003-06-12 US claimed
WO-2003045338-A1 COMPOSITIONS COMPRISING PHENYL-GLYCINE DERIVATIVES YU RUEY J (US) 2003-06-05 WO claimed
US-20030045725-A1 Method for the production of aromatic or heteroaromatic aldehydes or ketones by oxidative decarboxylation DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) 2003-03-06 US claimed
EP-0173921-B1 PROCESS FOR THE RACEMIZATION OF AN ALPHA-AMINO ACID BEECHAM GROUP PLC (GB) 1988-05-18 EP claimed
US-4647692-A Racemization and resolution of α-amino acids BEECHAM GROUP P.L.C. (GB) 1987-03-03 US claimed
EP-0173921-A1 Process for the racemization of an alpha-amino acid BEECHAM GROUP PLC (GB) 1986-03-12 EP claimed
EP-0164026-A1 Process for the preparation of optically active glycine derivatives BEECHAM GROUP PLC (GB) 1985-12-11 EP claimed
CN-119523843-A Skin care sun protection emulsion and preparation method and application thereof 广州芊植本草化妆品有限公司 2025-02-28 CN disclosed
CN-119523843-A Skin care sun protection emulsion and preparation method and application thereof 广州芊植本草化妆品有限公司 2025-02-28 CN disclosed
CN-117305193-A Recombinant bacterium for producing hydroxyl-containing benzoic acid and derivative thereof, construction method and application thereof 杭州唯铂莱生物科技有限公司 2023-12-29 CN disclosed
US-20230292741-A1 NOVEL SUPERCOOLING METHODS FOR PRESERVATION OF BIOLOGICAL SAMPLES X-THERMA, INC. (US) 2023-09-21 US disclosed
US-4175206-A Process for preparing a hydroxyphenylglycine compound TANABE SEIYAKU CO., LTD. (JP) 1979-11-20 US disclosed
US-4105690-A CONDENSATION NOBEL HOECHST CHIMIE (FR) 1978-08-08 US disclosed
US-3985739-A 3-Heterocyclic thiomethylcephalosporins SMITHKLINE CORPORATION (US) 1976-10-12 US disclosed
US-3968226-A 3-Heterocyclic thiomethylcephalosporins as antibacterial agents SMITHKLINE CORPORATION (US) 1976-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030108496-A1 Compositions comprising phenyl-glycine derivatives GRHPR, ARL1, SUCLG1 ERCC1 3009/4885ERCC4 2755/4885ARG1 163/4885
US-20230292741-A1 NOVEL SUPERCOOLING METHODS FOR PRESERVATION OF BIOLOGICAL SAMPLES PPIG, AQP3, AQP1 ERCC1 431/4885ERCC4 396/4885ARG1 2876/4885
US-20030045725-A1 Method for the production of aromatic or heteroaromatic aldehydes or ketones by oxidative decarboxylation AOX1, ALDH5A1, AOC2 ERCC1 3503/4885ERCC4 3176/4885ARG1 1733/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.