SCHEMBL1930853

SCHEMBL1930853

O=C(O)CNc1ccc(CC(=O)O)c(O)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ EGFR P00533 2/20 0.53
▸ AKR1B1 P15121 1/20 0.46
▸ HSD17B14 Q9BPX1 1/20 0.44
▸ ERCC1 P07992 1/20 0.44
▸ ERCC4 Q92889 1/20 0.44
▸ RGS12 O14924 2/20 0.39
▸ MAPT P10636 2/20 0.39
▸ TDP1 Q9NUW8 2/20 0.39
▸ POLB P06746 2/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ LMNA P02545 1/20 0.39
▸ GAA P10253 1/20 0.39
▸ HPGD P15428 1/20 0.39
▸ TSHR P16473 1/20 0.39
▸ NFKB1 P19838 1/20 0.39
▸ APEX1 P27695 1/20 0.39
▸ THPO P40225 1/20 0.39
▸ BLM P54132 1/20 0.39
▸ GNAI1 P63096 1/20 0.39
▸ PMP22 Q01453 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8074105 0.88 HSD17B14 (0.43) EGFRHSD17B14ERCC1ERCC4RGS12
SCHEMBL851008 0.83 ERCC1 (0.60) EGFRHSD17B14ERCC1ERCC4RGS12
SCHEMBL1930556 0.83 SMN1; SMN2 (0.46) EGFRMAPTKDM4EGAAALDH1A1
Water SCHEMBL9710740 0.81 ERCC1 (0.58) EGFRHSD17B14ERCC1ERCC4RGS12
SCHEMBL15933411 0.79 ALDH1A1 (0.53) HSD17B14ERCC1ERCC4MAPTTDP1
SCHEMBL11532312 0.79 HSD17B14 (0.50) EGFRHSD17B14ERCC1ERCC4RGS12
SCHEMBL155359 0.79 KMT2A (0.53) EGFRERCC1ERCC4RGS12MAPT
SCHEMBL8668410 0.76 EGFR (0.40) EGFRHSD17B14MAPTKDM4ELMNA
SCHEMBL5692310 0.76 ALDH1A1 (0.44) ERCC1ERCC4MAPTPOLBLMNA
SCHEMBL7628128 0.76 EGFR (0.43) EGFRAKR1B1HSD17B14MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1975707-B1 Curable composition and planographic printing plate precursor FUJIFILM CORP (JP) 2017-07-19 — — EP disclosed
EP-1801651-B1 Polymerizable composition and planographic printing plate precursor using the same FUJIFILM CORP (JP) 2017-04-19 — — EP disclosed
EP-2039509-B1 Curable composition, image forming material, and planographic printing plate precursor FUJIFILM CORP (JP) 2014-03-26 — — EP disclosed
EP-1862301-B1 Image recording material, planographic printing plate precursor, and planographic printing method using the same FUJIFILM CORP (JP) 2011-09-28 — — EP disclosed
US-7964334-B2 Mixture containing urea compound as photoinitiator; curing by exposure to laser light FUJIFILM CORPORATION (JP) 2011-06-21 — — US disclosed
US-7955781-B2 Negative-working photosensitive material and negative-working planographic printing plate precursor FUJIFILM CORPORATION (JP) 2011-06-07 — — US disclosed
EP-2042928-B1 Negative-working photosensitive material and negative-working planographic printing plate precursor FUJIFILM CORP (JP) 2010-07-28 — — EP disclosed
EP-2042522-B1 Planographic printing plate precursor FUJIFILM CORP (JP) 2010-07-14 — — EP disclosed
EP-1901124-B1 Image recording material FUJIFILM CORP (JP) 2010-06-30 — — EP disclosed
US-7723011-B2 Support, protective layer of crosslinked polymer ionically crosslinkable; ethylenically unsaturated polymerization initiator, binder polymer, dye; direct plate-making negative-working lithographic printing plate precursor; directly making a plate with a laser from a digital signal of a computer FUJIFILM CORPORATION (JP) 2010-05-25 — — US disclosed
EP-2042309-A2 Method of producing a negative planographic printing plate FUJIFILM Corporation (JP) 2009-04-01 — — EP disclosed
EP-2042522-A1 Curable composition, image forming material, and planographic printing plate precursor FUJIFILM Corporation (JP) 2009-04-01 — — EP disclosed
EP-2039509-A1 Curable composition, image forming material, and planographic printing plate precursor FUJIFILM Corporation (JP) 2009-03-25 — — EP disclosed
US-20080241744-A1 CURABLE COMPOSITION AND PLANOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2008-10-02 — — US disclosed
EP-1975707-A1 Curable composition and planographic printing plate precursor Fujifilm Corporation (JP) 2008-10-01 — — EP disclosed
US-20080145782-A1 IMAGE RECORDING MATERIAL AND NOVEL COMPOUND FUJIFILM CORPORATION (JP) 2008-06-19 — — US disclosed
EP-1930770-A2 Imaging recording material and novel compound FUJIFILM Corporation (JP) 2008-06-11 — — EP disclosed
EP-1901124-A1 Image recording material FUJIFILM Corporation (JP) 2008-03-19 — — EP disclosed
EP-1862301-A1 Image recording material, planographic printing plate precursor, and planographic printing method using the same FUJIFILM Corporation (JP) 2007-12-05 — — EP disclosed
EP-1801651-A1 Polymerizable composition and planographic printing plate precursor using the same Fujifilm Corporation (JP) 2007-06-27 — — EP disclosed
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