Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1026968 | 1.00 | CFTR (0.43) | CFTRGOPCALDH1A1SIGMAR1KMT2A | |
| SCHEMBL28270428 | 0.89 | ALDH1A1 (0.48) | CFTRGOPCALDH1A1KMT2APTGS2 | |
| SCHEMBL28271995 | 0.84 | TAAR1 (0.53) | CFTRGOPCALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL23092049 | 0.79 | MAPK1 (0.48) | CFTRGOPCALDH1A1RAB9AMAPT | |
| SCHEMBL28270479 | 0.79 | CYP1A2 (0.44) | KMT2ANPC1RAB9ACYP11B1CYP11B2 | |
| SCHEMBL28270417 | 0.77 | ALDH1A1 (0.46) | ALDH1A1KMT2AMAPTSMN1; SMN2HPGD | |
| Hydrochloric Acid SCHEMBL3370517 | 0.74 | CFTR (0.35) | CFTRGOPCALDH1A1SIGMAR1HTR2C | |
| Hydrochloric Acid SCHEMBL3370512 | 0.74 | CYP11B1 (0.33) | CFTRGOPCALDH1A1SIGMAR1HTR2C | |
| Hydrochloric Acid SCHEMBL3370098 | 0.74 | CFTR (0.40) | CFTRGOPCALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL3370096 | 0.74 | CFTR (0.40) | CFTRGOPCALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6455458-B1 | HIGH MOLECULAR WEIGHT POLYOLEFIN; GROUP 4 TRANSITION METAL COMPLEXES HAVING A BIDENTATE ANCILLARY LIGAND SYSTEM OF ONE CYCLOPENTADIENYL GROUP BOUND TO THE TRANSITION METAL AND A GROUP 15 OR GROUP 16 ATOM COVALENTLY BOUND THROUGH A BRIDGING | EXXONMOBIL CHEMICAL PATENTS INC. | 2002-09-24 | — | — | US | disclosed |