SCHEMBL7628246

SCHEMBL7628246

CCCCN(CCC=O)CCCC

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.55
ALDH1A1 P00352 1/20 0.46
FAAH O00519 2/20 0.44
TRPV1 Q8NER1 2/20 0.44
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA9 Q16790 2/20 0.38
ADH1B P00325 2/20 0.37
ADH1C P00326 2/20 0.37
ADH1A P07327 2/20 0.37
ADH7 P40394 2/20 0.37
HIF1A Q16665 1/20 0.36
KDM5A P29375 3/20 0.36
EPHX1 P07099 1/20 0.36
ADH4 P08319 1/20 0.36
PHF8 Q9UPP1 2/20 0.34
KDM4C Q9H3R0 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29950905 0.91 TSHR (0.50) TSHRALDH1A1FAAHTRPV1CA12
Butanal SCHEMBL28067135 0.90 ALDH1A1 (0.60) TSHRALDH1A1FAAHTRPV1CA12
SCHEMBL7677802 0.90 TSHR (0.62) TSHRALDH1A1FAAHTRPV1CA12
SCHEMBL29957351 0.89 TSHR (0.44) TSHRALDH1A1FAAHTRPV1CA12
SCHEMBL7674518 0.88 TSHR (0.61) TSHRALDH1A1FAAHTRPV1CA12
SCHEMBL2439295 0.84 ALDH1A1 (0.50) TSHRALDH1A1FAAHTRPV1CA12
SCHEMBL23558779 0.83 TDP1 (0.40) TSHRALDH1A1FAAHTRPV1CA12
SCHEMBL9431925 0.83 TSHR (0.61) TSHRALDH1A1FAAHTRPV1ADH1B
Formic Acid SCHEMBL9721362 0.82 CA12 (0.44) TSHRALDH1A1CA12CA1CA9
SCHEMBL11146496 0.82 TSHR (0.48) TSHRALDH1A1FAAHTRPV1ADH1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6380197-B1 FOR TREATING AND PREVENTING A PLETHORA OF DISEASES INCLUDING DIABETES AVENTIS PHARMA S. A. (FR) 2002-04-30 US claimed
EP-1001943-A1 POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM Aventis Pharma S.A. (FR) 2000-05-24 EP claimed
WO-1999003843-A1 POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM RHONE-POULENC RORER S.A. (FR) 1999-01-28 WO claimed
US-9765224-B2 Anti-fogging film-forming material, coating liquid for forming anti-fogging film, anti-fogging article, and methods for producing these CENTRAL GLASS COMPANY, LIMITED (JP) 2017-09-19 US disclosed
CN-106659948-A Filter medium, method for producing filter medium, module for water treatment, and water treatment device 三菱综合材料株式会社 2017-05-10 CN disclosed
CN-106573185-A Oil and water separation device and drainage system 三菱综合材料株式会社 2017-04-19 CN disclosed
CN-106574165-A Hydrophilic oil repellent agent and method for manufacturing same, and surface covering material, coating film, resin composition, oil-water separation filter medium, and porous body 三菱综合材料株式会社 2017-04-19 CN disclosed
EP-2868723-A1 ANTI-FOGGING FILM-FORMING MATERIAL, COATING LIQUID FOR FORMING ANTI-FOGGING FILM, ANTI-FOGGING ARTICLE, AND METHODS FOR PRODUCING THESE Central Glass Co., Ltd. (JP) 2015-05-06 EP disclosed
US-20150111043-A1 Anti-Fogging Film-Forming Material, Coating Liquid for Forming Anti-Fogging Film, Anti-Fogging Article, and Methods for Producing These CENTRAL GLASS COMPANY, LIMITED (JP) 2015-04-23 US disclosed
US-6444852-B1 Amines useful in inhibiting gas hydrate formation GOLDSCHMIDT CHEMICAL CORPORATION 2002-09-03 US disclosed
US-6380197-B1 FOR TREATING AND PREVENTING A PLETHORA OF DISEASES INCLUDING DIABETES AVENTIS PHARMA S. A. (FR) 2002-04-30 US disclosed
EP-1001943-A1 POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM Aventis Pharma S.A. (FR) 2000-05-24 EP disclosed
WO-1999003843-A1 POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM RHONE-POULENC RORER S.A. (FR) 1999-01-28 WO disclosed