Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 6/20 | 0.42 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
| ▸ | NQO1 | P15559 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5032934 | 0.76 | TRPM4 (0.48) | TRPM4NQO2ALDH1A1CYP1A2KMT2A | |
| SCHEMBL29019737 | 0.71 | TRPM4 (0.43) | TRPM4NQO2ALDH1A1CYP1A2KMT2A | |
| SCHEMBL692620 | 0.70 | MEN1 (0.50) | TRPM4NQO2ALDH1A1CYP1A2KMT2A | |
| SCHEMBL5411002 | 0.69 | KDM4E (0.43) | TRPM4NQO2ALDH1A1CYP1A2KMT2A | |
| SCHEMBL6631799 | 0.69 | CYP2D6 (0.47) | TRPM4NQO2ALDH1A1CYP1A2KMT2A | |
| SCHEMBL342713 | 0.67 | ERN1 (0.41) | ERN1ALDH1A1CYP1A2KMT2AHSD17B10 | |
| SCHEMBL5888951 | 0.67 | TRPM4 (0.36) | TRPM4NQO2ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL7565940 | 0.66 | TRPM4 (0.38) | TRPM4NQO2ALDH1A1CYP1A2KMT2A | |
| SCHEMBL5841822 | 0.65 | ERN1 (0.63) | ERN1TRPM4NQO2CYP1A2KDM4E | |
| SCHEMBL3268303 | 0.65 | NQO2 (0.55) | ERN1TRPM4NQO2ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410766-B1 | — | — | None | — | — | US | disclosed |
| US-6410766-B2 | AN ORGANOMETALLIC COMPLEX CONTAINING A HYDROXYQUINOLINE OR 2-(O-HYDROXYPHENYL)-BENZOXAZOLE BIDENTATE LIGAND AND SECOND AND THIRD LIGAND IS A SUBSTITUTED OR NONSUBSTITUTED ARYL GROUP; THREE CHELATE ATOMS, TWO OXYGEN AND ONE NITROGEN ATOM | TSINGHAU UNIVERSITY (CN) | 2002-06-25 | — | — | US | disclosed |
| US-20010037024-A1 | Emitting materials used for organic EL based on tridentate ligands | TSINGHUA UNIVERSITY (CN) | 2001-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010037024-A1 | Emitting materials used for organic EL based on tridentate ligands | SLC1A1, SLCO2A1, SLCO1A2 | ERN1 3335/4885TRPM4 794/4885NQO2 2479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.