Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | CCKAR | P32238 | 1/20 | 0.33 |
| ▸ | CCKBR | P32239 | 1/20 | 0.33 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5855675 | 0.86 | NPC1 (0.39) | NPC1RAB9ACYP2C19ALDH1A1KDM4E | |
| SCHEMBL5854780 | 0.86 | NPC1 (0.39) | NPC1RAB9ACYP2C19ALDH1A1KDM4E | |
| SCHEMBL5852838 | 0.85 | NPC1 (0.40) | NPC1RAB9ACYP2C19ALDH1A1KDM4E | |
| SCHEMBL7626477 | 0.84 | NPC1 (0.38) | NPC1RAB9ACYP2C19ALDH1A1KDM4E | |
| SCHEMBL7633227 | 0.83 | ALDH1A1 (0.39) | NPC1RAB9ACYP2C19ALDH1A1KDM4E | |
| SCHEMBL5854766 | 0.78 | HPGD (0.39) | NPC1RAB9ACYP2C19ALDH1A1KDM4E | |
| SCHEMBL5854870 | 0.78 | HPGD (0.39) | NPC1RAB9ACYP2C19ALDH1A1KDM4E | |
| SCHEMBL5853516 | 0.77 | HPGD (0.37) | NPC1RAB9ACYP2C19ALDH1A1HPGD | |
| SCHEMBL9587137 | 0.72 | NPC1 (0.41) | NPC1RAB9ACYP2C19ALDH1A1KDM4E | |
| SCHEMBL6857282 | 0.72 | NPC1 (0.43) | NPC1RAB9ACYP2C19ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0849288-B1 | Catalyst for polymerization of an olefin, and method for producing an olefin polymer | TOSOH CORP (JP) | 2002-11-27 | — | — | EP | disclosed |
| US-5906955-A | Catalyst for polymerization of an olefin, and method for producing an olefin polymer | TOSOH CORPORATION (JP) | 1999-05-25 | — | — | US | disclosed |
| EP-0849288-A1 | Catalyst for polymerization of an olefin, and method for producing an olefin polymer | TOSOH CORPORATION (JP) | 1998-06-24 | — | — | EP | disclosed |