Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6692031 | 0.76 | RAB9A (0.41) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL7627840 | 0.72 | NPC1 (0.40) | NPC1RAB9ACYP2C19SMN1; SMN2HPGD | |
| SCHEMBL7628547 | 0.72 | NPC1 (0.40) | NPC1RAB9ACYP2C19SMN1; SMN2HPGD | |
| SCHEMBL6857282 | 0.72 | NPC1 (0.43) | NPC1RAB9ACYP2C19SMN1; SMN2HPGD | |
| SCHEMBL5854820 | 0.72 | NPC1 (0.39) | NPC1RAB9ACYP2C19SMN1; SMN2HPGD | |
| SCHEMBL5853698 | 0.72 | NPC1 (0.39) | NPC1RAB9ACYP2C19SMN1; SMN2HPGD | |
| SCHEMBL5856430 | 0.72 | NPC1 (0.39) | NPC1RAB9ACYP2C19SMN1; SMN2HPGD | |
| SCHEMBL5854780 | 0.72 | NPC1 (0.39) | NPC1RAB9ACYP2C19SMN1; SMN2HPGD | |
| SCHEMBL5853858 | 0.72 | NPC1 (0.39) | NPC1RAB9ACYP2C19SMN1; SMN2HPGD | |
| SCHEMBL5855675 | 0.72 | NPC1 (0.39) | NPC1RAB9ACYP2C19SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993021242-A1 | ETHYLENE/BRANCHED OLEFIN COPOLYMERS | EXXON CHEMICAL PATENTS INC. (US) | 1993-10-28 | — | — | WO | disclosed |