Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 3/20 | 0.47 |
| ▸ | MMP3 | P08254 | 3/20 | 0.47 |
| ▸ | MMP9 | P14780 | 3/20 | 0.47 |
| ▸ | MMP13 | P45452 | 2/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7633124 | 0.94 | LMNA (0.50) | ALDH1A1LMNAMMP2MMP3MMP9 | |
| SCHEMBL7626722 | 0.89 | ALDH1A1 (0.59) | ALDH1A1LMNAMMP2MMP3MMP9 | |
| SCHEMBL7628589 | 0.88 | SMN1; SMN2 (0.51) | ALDH1A1LMNAMMP2MMP3MMP9 | |
| SCHEMBL7623455 | 0.87 | F10 (0.53) | ALDH1A1MMP2MMP3MMP9MMP13 | |
| SCHEMBL7630081 | 0.86 | MMP2 (0.50) | ALDH1A1LMNAMMP2MMP3MMP9 | |
| SCHEMBL7627770 | 0.84 | MCHR1 (0.58) | LMNAMMP2MMP3MMP9MMP13 | |
| SCHEMBL7629877 | 0.83 | MMP2 (0.43) | ALDH1A1LMNAMMP2MMP3MMP9 | |
| SCHEMBL7631288 | 0.82 | CD274 (0.54) | ALDH1A1HPGDMAPTHTTSMN1; SMN2 | |
| SCHEMBL7352438 | 0.81 | MMP2 (0.60) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL7347169 | 0.81 | MMP2 (0.60) | MMP2MMP3MMP9MMP13MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0907632-B1 | INHIBITION OF MATRIX METALLOPROTEASES BY SUBSTITUTED PHENETHYL COMPOUNDS | BAYER AG (US) | 2002-12-11 | — | — | EP | disclosed |