Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 3/20 | 0.30 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9344212 | 0.79 | SIGMAR1 (0.37) | GPR84ALDH1A1TSHRPCSK9LTA4H | |
| SCHEMBL6276812 | 0.76 | TSHR (0.34) | SMN1; SMN2ALDH1A1MAPTTSHRPCSK9 | |
| SCHEMBL3726383 | 0.76 | TSHR (0.34) | SMN1; SMN2ALDH1A1MAPTTSHRPCSK9 | |
| SCHEMBL9763717 | 0.73 | ESR1 (0.37) | TSHRLMNA | |
| SCHEMBL4930368 | 0.71 | TSHR (0.35) | GPR84ALDH1A1MAPTTSHRPCSK9 | |
| SCHEMBL15094093 | 0.71 | SMN1; SMN2 (0.36) | SMN1; SMN2ALDH1A1TSHRLMNA | |
| SCHEMBL272398 | 0.71 | PCSK9 (0.39) | ALDH1A1TSHRPCSK9NAAAAR | |
| SCHEMBL3886636 | 0.70 | TSHR (0.38) | SMN1; SMN2TSHRPCSK9LTA4HNAAA | |
| SCHEMBL27604670 | 0.70 | TSHR (0.38) | SMN1; SMN2TSHRPCSK9LTA4HNAAA | |
| SCHEMBL5801979 | 0.69 | NR1H2 (0.53) | MAPTTSHRPCSK9LTA4HNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6451766-B1 | SIALIDASE INHIBITORS; INFLUENZA VIRICIDES | SANKYO COMPANY, LIMITED (JP) | 2002-09-17 | — | — | US | disclosed |