Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5180601 | 0.77 | ESR1 (0.37) | ESR1ESR2TDP1TAAR1LMNA | |
| SCHEMBL985723 | 0.77 | ESR1 (0.37) | ESR1ESR2TDP1TAAR1LMNA | |
| SCHEMBL13766348 | 0.77 | ESR1 (0.37) | ESR1ESR2TDP1TAAR1LMNA | |
| SCHEMBL23557563 | 0.74 | ESR1 (0.41) | ESR1ESR2TDP1TAAR1LMNA | |
| SCHEMBL14959333 | 0.74 | ESR1 (0.41) | ESR1ESR2TDP1TAAR1LMNA | |
| SCHEMBL7628573 | 0.73 | GPR84 (0.35) | LMNATSHR | |
| SCHEMBL15915541 | 0.72 | POLB (0.35) | ESR1ESR2TDP1TAAR1LMNA | |
| SCHEMBL706818 | 0.72 | MAOA (0.36) | ESR1ESR2TDP1TAAR1LMNA | |
| SCHEMBL705009 | 0.72 | ESR1 (0.34) | ESR1ESR2TDP1TAAR1LMNA | |
| SCHEMBL711378 | 0.72 | ESR1 (0.34) | ESR1ESR2TDP1TAAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996341-A | Condensed bicyclic disilanylene-acetylene compound and method for preparing the same | KANEGAFUCHI CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-02-26 | — | — | US | disclosed |