SCHEMBL7628574

SCHEMBL7628574

CC(=O)OC1C=CCC2C(=O)c3cccc(O)c3C(=O)C12

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NSD2 O96028 1/20 0.70
HK1 P19367 1/20 0.70
HKDC1 Q2TB90 1/20 0.70
PIM1 P11309 2/20 0.46
IDO1 P14902 2/20 0.36
MAOA P21397 4/20 0.33
STAT3 P40763 2/20 0.33
P4HB P07237 3/20 0.33
PDIA4 P13667 3/20 0.33
PDIA3 P30101 3/20 0.33
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
POLB P06746 1/20 0.33
MAOB P27338 3/20 0.33
ALDH1A1 P00352 3/20 0.33
MAPT P10636 3/20 0.33
HPGD P15428 3/20 0.33
ALOX15 P16050 3/20 0.33
MAPK1 P28482 3/20 0.33
HSD17B10 Q99714 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7637697 0.95 NSD2 (0.77) NSD2HK1HKDC1PIM1IDO1
SCHEMBL11832717 0.86 NSD2 (0.70) NSD2HK1HKDC1STAT3MEN1
SCHEMBL7637705 0.80 PIM1 (0.51) NSD2HK1HKDC1PIM1IDO1
SCHEMBL7633252 0.75 NSD2 (0.51) NSD2HK1HKDC1PIM1IDO1
SCHEMBL11022246 0.70 NSD2 (0.51) NSD2HK1HKDC1
SCHEMBL11019899 0.70 NSD2 (0.54) NSD2HK1HKDC1
SCHEMBL10633275 0.69 NSD2 (0.49) NSD2HK1HKDC1
SCHEMBL10903809 0.69 NSD2 (0.49) NSD2HK1HKDC1
SCHEMBL6215321 0.68 NSD2 (0.48) NSD2HK1HKDC1
SCHEMBL17195889 0.65 NSD2 (0.46) NSD2HK1HKDC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0525073-B1 ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA DU PONT (US) 1994-05-25 EP claimed
EP-0525073-A1 ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA. DU PONT (US) 1993-02-03 EP claimed
WO-1991015954-A1 ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-10-31 WO claimed
US-20250302797-A1 COMBINATION THERAPIES FOR TREATING INFLAMMATION FLAGSHIP PIONEERING INNOVATIONS VI LLC (US) 2025-10-02 US disclosed
EP-0801639-B1 METHOD FOR PREPARING SUBSTITUTED ANTHRAQUINONES AND USE THEREOF FOR PREPARING RHEINS GIREX (FR) 2002-01-02 EP disclosed
US-5948924-A Process for the preparation of substituted anthraquinones and application in the preparation of rheins GIREX (SOCIETE ANONYME) (FR) 1999-09-07 US disclosed
US-5385842-A Anthraquinones as inhibitors of sulfide production from sulfate-reducing bacteria E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-01-31 US disclosed
EP-0525073-B1 ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA DU PONT (US) 1994-05-25 EP disclosed
WO-1991015954-A1 ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-10-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250302797-A1 COMBINATION THERAPIES FOR TREATING INFLAMMATION TNF, MMP8, TSLP NSD2 3273/4885HK1 1311/4885HKDC1 968/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.