Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 3/20 | 0.51 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | HK1 | P19367 | 1/20 | 0.46 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 4/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7633252 | 0.95 | NSD2 (0.51) | PIM1NSD2HK1HKDC1IDO1 | |
| SCHEMBL7624596 | 0.83 | PIM1 (0.51) | PIM1NSD2HK1HKDC1IDO1 | |
| SCHEMBL7628574 | 0.80 | NSD2 (0.70) | PIM1NSD2HK1HKDC1IDO1 | |
| SCHEMBL7624508 | 0.79 | PIM1 (0.46) | PIM1NSD2HK1HKDC1IDO1 | |
| SCHEMBL7637697 | 0.75 | NSD2 (0.77) | PIM1NSD2HK1HKDC1IDO1 | |
| SCHEMBL11832717 | 0.64 | NSD2 (0.70) | NSD2HK1HKDC1STAT3MEN1 | |
| SCHEMBL10636266 | 0.62 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL31199228 | 0.62 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL28137965 | 0.61 | STAT3 (0.54) | PIM1IDO1STAT3MAOAMAOB | |
| SCHEMBL9389657 | 0.60 | MAOA (0.54) | PIM1IDO1STAT3MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801639-B1 | METHOD FOR PREPARING SUBSTITUTED ANTHRAQUINONES AND USE THEREOF FOR PREPARING RHEINS | GIREX (FR) | 2002-01-02 | — | — | EP | disclosed |
| US-5948924-A | Process for the preparation of substituted anthraquinones and application in the preparation of rheins | GIREX (SOCIETE ANONYME) (FR) | 1999-09-07 | — | — | US | disclosed |