Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.56 |
| ▸ | HTR1A | P08908 | 3/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10750642 | 0.84 | SMN1; SMN2 (0.46) | SIGMAR1GRIN2B | |
| SCHEMBL8510380 | 0.81 | CA2 (0.50) | SIGMAR1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL967958 | 0.81 | CA2 (0.50) | SIGMAR1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL968880 | 0.81 | HTR1A (0.51) | SIGMAR1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL9153673 | 0.81 | HTR1A (0.66) | SIGMAR1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL9153669 | 0.81 | HTR1A (0.66) | SIGMAR1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL7632498 | 0.81 | TDP1 (0.44) | — | |
| SCHEMBL7634476 | 0.81 | DRD2 (0.39) | — | |
| SCHEMBL3641960 | 0.80 | CYP1A2 (0.51) | SIGMAR1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL6918962 | 0.80 | CA2 (0.52) | SIGMAR1HTR1AADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1182129-C | Benzopyran derivatives having leukotriene-antagonistic action | ������ʵ���ҹ�˾ | 2004-12-29 | — | — | CN | disclosed |
| EP-0888327-B1 | BENZOPYRAN DERIVATIVES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | MENARINI LAB (ES) | 2002-06-12 | — | — | EP | disclosed |
| US-5990142-A | ANTIINFLAMMATORY AGENTS AND ANTIALLERGENS HAVING GOOD ORAL ADSORPTION AND BIOAVAILABILITY; CARDIOTONIC AND ANTIISCHEMIC AGENTS | LABORATORIOS MENARINI S.A. (ES) | 1999-11-23 | — | — | US | disclosed |
| CN-1214048-A | Benzopyran derivatives having leukotriene-antagonistic action | LABROATORIOS MENARINI S A (ES) | 1999-04-14 | — | — | CN | disclosed |
| EP-0888327-A1 | BENZOPYRAN DERIVATIVES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997034885-A1 | BENZOPYRAN DERIVATIVES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1997-09-25 | — | — | WO | disclosed |