SCHEMBL762878

SCHEMBL762878

Brc1ccc(Br)c2nc3c4ccccc4c4ccccc4c3nc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 4/20 0.47
MAPT P10636 5/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
LMNA P02545 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
POLB P06746 1/20 0.41
PKM P14618 1/20 0.41
BLM P54132 1/20 0.41
ALDH1A1 P00352 6/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
PRNP P04156 1/20 0.38
HPGD P15428 1/20 0.38
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CYP1A2 P05177 3/20 0.37
ADORA1 P30542 1/20 0.37
HPRT1 P00492 1/20 0.36
APAF1 O14727 1/20 0.35
TDP2 O95551 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL668870 0.84 ALDH1A1 (0.50) NQO2MAPTMEN1KMT2ALMNA
SCHEMBL29212039 0.82 KMT2A (0.52) NQO2MAPTMEN1KMT2ALMNA
SCHEMBL30870065 0.82 KMT2A (0.52) NQO2MAPTMEN1KMT2ALMNA
SCHEMBL11795067 0.81 MAPT (0.48) NQO2MAPTMEN1KMT2ALMNA
SCHEMBL30471900 0.81 MAPT (0.48) NQO2MAPTMEN1KMT2ALMNA
SCHEMBL12355748 0.81 MAPT (0.48) NQO2MAPTMEN1KMT2ALMNA
SCHEMBL12657684 0.78 NQO2 (0.46) NQO2BACE1
SCHEMBL13293060 0.74 ALDH1A1 (0.48) NQO2MAPTMEN1KMT2ALMNA
SCHEMBL19988780 0.74 NQO2 (0.75) NQO2MAPTKMT2ATDP1ALDH1A1
SCHEMBL18805402 0.72 MYC (0.52) NQO2MAPTMEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2041200-B1 NOVEL ELECTROLUMINESCENT POLYMERS FOR ELECTRONIC APPLICATIONS UDC IRELAND LTD (IE) 2018-03-07 EP disclosed
EP-2514736-B1 Intermediates for Polymers BASF SE (DE) 2017-03-01 EP disclosed
US-9296848-B2 Polymer material, solar cell using the same, and solar photovoltaic generation system KABUSHIKI KAISHA TOSHIBA (JP) 2016-03-29 US disclosed
US-9296848-B2 Polymer material, solar cell using the same, and solar photovoltaic generation system KABUSHIKI KAISHA TOSHIBA (JP) 2016-03-29 US disclosed
US-8445630-B2 Polymers BASF SE (DE) 2013-05-21 US disclosed
US-8445630-B2 Polymers BASF SE (DE) 2013-05-21 US disclosed
EP-2514736-A1 Intermediates for Polymers BASF SE (DE) 2012-10-24 EP disclosed
US-20120248878-A1 POLYMER MATERIAL, SOLAR CELL USING THE SAME, AND SOLAR PHOTOVOLTAIC GENERATION SYSTEM KABUSHIKI KAISHA TOSHIBA (JP) 2012-10-04 US disclosed
US-20120248878-A1 POLYMER MATERIAL, SOLAR CELL USING THE SAME, AND SOLAR PHOTOVOLTAIC GENERATION SYSTEM KABUSHIKI KAISHA TOSHIBA (JP) 2012-10-04 US disclosed
US-8221906-B2 Electroluminescent polymers for electronic applications BASF SE (DE) 2012-07-17 US disclosed
US-20090203866-A1 Novel Polymers BASF SE (DE) 2009-08-13 US disclosed
US-20090203866-A1 Novel Polymers BASF SE (DE) 2009-08-13 US disclosed
US-20090105447-A1 Novel Polymers UDC IRELAND LIMITED (IE) 2009-04-23 US disclosed
US-20090105447-A1 Novel Polymers UDC IRELAND LIMITED (IE) 2009-04-23 US disclosed
EP-1956011-A1 AMINE COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME Idemitsu Kosan Co., Ltd. (JP) 2008-08-13 EP disclosed
WO-2008012250-A1 NOVEL POLYMERS CIBA HOLDING INC. (CH) 2008-01-31 WO disclosed
WO-2008006743-A1 NOVEL ELECTROLUMINESCENT POLYMERS FOR ELECTRONIC APPLICATIONS CIBA HOLDING INC (CH) 2008-01-17 WO disclosed
WO-2007090773-A1 NOVEL POLYMERS CIBA HOLDING INC. (CH) 2007-08-16 WO disclosed
US-20070132372-A1 AMINE BASED COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-06-14 US disclosed
US-20070132372-A1 AMINE BASED COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090105447-A1 Novel Polymers PLEC, VIM, PUF60 NQO2 1861/4885MAPT 123/4885MEN1 3994/4885
US-20070132372-A1 AMINE BASED COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME KCNH2, SLC7A5, KCNH3 NQO2 171/4885MAPT 1443/4885MEN1 1092/4885
US-20090203866-A1 Novel Polymers PLEC, PUF60, VIM NQO2 1970/4885MAPT 32/4885MEN1 3935/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.