Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9893591 | 0.88 | HSD17B10 (0.47) | HSD17B10TSHRCYP3A4MAPK1L3MBTL1 | |
| SCHEMBL9893546 | 0.79 | TSHR (0.56) | HSD17B10TSHRCYP3A4MAPK1L3MBTL1 | |
| SCHEMBL3731188 | 0.78 | TP53 (0.41) | TSHRMAPK1HPGDALDH1A1TDP1 | |
| SCHEMBL2317562 | 0.78 | TP53 (0.45) | HSD17B10TSHRMAPK1L3MBTL1HPGD | |
| SCHEMBL29853674 | 0.78 | TP53 (0.45) | HSD17B10TSHRMAPK1L3MBTL1HPGD | |
| SCHEMBL5665402 | 0.77 | ALDH1A1 (0.54) | HSD17B10TSHRCYP3A4MAPK1L3MBTL1 | |
| SCHEMBL19009447 | 0.76 | L3MBTL1 (0.47) | HSD17B10TSHRCYP3A4MAPK1L3MBTL1 | |
| SCHEMBL4646487 | 0.76 | HSD17B10 (0.43) | HSD17B10TSHRCYP3A4MAPK1L3MBTL1 | |
| SCHEMBL19009444 | 0.74 | TYMS (0.47) | HSD17B10TSHRCYP3A4MAPK1L3MBTL1 | |
| SCHEMBL15412100 | 0.74 | TSHR (0.41) | HSD17B10TSHRCYP3A4MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6451341-B1 | ADMINISTERING TO ANIMAL DIETARY SUPPLEMENT COMPRISING BUTYLATED HYDROXYTOLUENE(BHT), BUTYLATED HYDROXYANISOLE(BHA), VITAMIN E, AND B-CAROTENE TO PREVENT SKIN CANCER | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2002-09-17 | — | — | US | disclosed |