Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5730432 | 0.88 | MEN1 (0.47) | MEN1KMT2ATP53RXFP1ALDH1A1 | |
| SCHEMBL27691865 | 0.76 | MEN1 (0.53) | MEN1KMT2AALDH1A1HSD17B10HPGD | |
| SCHEMBL27673007 | 0.74 | MEN1 (0.48) | MEN1KMT2ATP53RXFP1SMN1; SMN2 | |
| SCHEMBL14581574 | 0.72 | MEN1 (0.52) | MEN1KMT2ATP53RXFP1ALDH1A1 | |
| SCHEMBL29557960 | 0.72 | PBRM1 (0.52) | MEN1KMT2ATP53RXFP1ALDH1A1 | |
| SCHEMBL15415994 | 0.72 | PBRM1 (0.52) | MEN1KMT2ATP53RXFP1ALDH1A1 | |
| SCHEMBL27148809 | 0.71 | SLC22A6 (0.50) | MEN1KMT2ATP53RXFP1ALDH1A1 | |
| SCHEMBL5729731 | 0.70 | POLB (0.52) | MEN1KMT2ASMN1; SMN2HTR2ANR4A2 | |
| SCHEMBL3224553 | 0.70 | MPO (0.49) | MEN1KMT2ASMN1; SMN2KDM4ETSHR | |
| Dimethylformamide SCHEMBL27597593 | 0.70 | SLC22A6 (0.46) | MEN1KMT2AALDH1A1KDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-86104611-A | The preparation method of therapeutical agent | — | 1988-01-27 | — | — | CN | claimed |
| EP-0206616-A2 | Quinolones having antihypertensive activity | The Boots Company PLC (GB) | 1986-12-30 | — | — | EP | claimed |
| US-6451813-B1 | Treatment of gastroparesis in certain patient groups | R. T. ALAMO VENTURES I, LLC | 2002-09-17 | — | — | US | disclosed |
| CN-86104611-A | The preparation method of therapeutical agent | — | 1988-01-27 | — | — | CN | disclosed |
| CN-86104611-A | The preparation method of therapeutical agent | — | 1988-01-27 | — | — | CN | disclosed |