Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6904665 | 0.82 | ABCC9 (0.40) | ALDH1A1MEN1KMT2AKDM4EPOLB | |
| SCHEMBL7241347 | 0.78 | ALDH1A1 (0.35) | ALDH1A1MEN1KMT2AKDM4EPOLB | |
| SCHEMBL7620062 | 0.70 | MAPT (0.41) | ALDH1A1MEN1KMT2AKDM4EPOLB | |
| SCHEMBL7236602 | 0.65 | ABCC9 (0.56) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL7625050 | 0.65 | ABCC9 (0.44) | ALDH1A1MEN1KMT2AKDM4EPOLB | |
| SCHEMBL7232996 | 0.65 | MAPT (0.42) | ALDH1A1MEN1KMT2AKDM4EPOLB | |
| SCHEMBL6432510 | 0.65 | ABCC9 (0.55) | ALDH1A1KMT2AKDM4EMAPTTDP1 | |
| SCHEMBL6465855 | 0.65 | ABCC9 (0.51) | — | |
| SCHEMBL6910686 | 0.65 | ABCC9 (0.55) | ALDH1A1KMT2AKDM4EMAPTTDP1 | |
| SCHEMBL6431863 | 0.65 | ABCC9 (0.66) | ALDH1A1KMT2AKDM4EMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194429-A1 | POTASSIUM CHANNEL OPENERS | Abbott Laboratories (US) | 2002-04-10 | — | — | EP | claimed |
| WO-2000078768-A1 | POTASSIUM CHANNEL OPENERS | ABBOTT LABORATORIES (US) | 2000-12-28 | — | — | WO | claimed |