Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14373959 | 1.00 | ALDH1A1 (0.45) | ALDH1A1MAPK1BACE1CRHBPCRHR2 | |
| SCHEMBL734059 | 0.87 | ALDH1A1 (0.56) | ALDH1A1MAPK1BACE1CRHBPCRHR2 | |
| SCHEMBL18828880 | 0.85 | ALDH1A1 (0.54) | ALDH1A1MAPK1BACE1CRHBPCRHR2 | |
| SCHEMBL14373924 | 0.83 | CRHBP (0.41) | ALDH1A1MAPK1CRHBPCRHR2AKR1C3 | |
| SCHEMBL12403015 | 0.83 | ALDH1A1 (0.52) | ALDH1A1MAPK1BACE1CRHBPCRHR2 | |
| SCHEMBL13141940 | 0.83 | BACE1 (0.46) | ALDH1A1MAPK1BACE1ALOX5HSD17B10 | |
| SCHEMBL12403069 | 0.79 | ALDH1A1 (0.48) | ALDH1A1MAPK1BACE1CRHBPCRHR2 | |
| SCHEMBL29405259 | 0.78 | ALDH1A1 (0.62) | ALDH1A1MAPK1BACE1CRHBPCRHR2 | |
| SCHEMBL735086 | 0.78 | ALDH1A1 (0.62) | ALDH1A1MAPK1BACE1CRHBPCRHR2 | |
| SCHEMBL2470342 | 0.78 | ALDH1A1 (0.62) | ALDH1A1MAPK1BACE1CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138355-B2 | Heteroacene derivative, tetrahaloterphenyl derivative, and processes for producing the same | TOSOH CORPORATION (JP) | 2012-03-20 | — | — | US | disclosed |
| US-20090261300-A1 | HETEROACENE DERIVATIVE, TETRAHALOTERPHENYL DERIVATIVE, AND PROCESSES FOR PRODUCING THE SAME | TOSOH CORPORATION (JP) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090261300-A1 | HETEROACENE DERIVATIVE, TETRAHALOTERPHENYL DERIVATIVE, AND PROCESSES FOR PRODUCING THE SAME | AS3MT, TERT, TEAD1 | ALDH1A1 2196/4885MAPK1 951/4885BACE1 1727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.