SCHEMBL7629632

SCHEMBL7629632

COc1ccc2c(c1)N(c1ccccc1)CCCC2

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TUBB4A P04350 8/20 0.50
TUBB P07437 8/20 0.50
TUBA3C P0DPH7 8/20 0.50
TUBA1B P68363 8/20 0.50
TUBA4A P68366 8/20 0.50
TUBB4B P68371 8/20 0.50
TUBB3 Q13509 8/20 0.50
TUBB2A Q13885 8/20 0.50
TUBB8 Q3ZCM7 8/20 0.50
TUBA3E Q6PEY2 8/20 0.50
TUBA1A Q71U36 8/20 0.50
TUBA1C Q9BQE3 8/20 0.50
TUBB6 Q9BUF5 8/20 0.50
TUBB2B Q9BVA1 8/20 0.50
TUBB1 Q9H4B7 8/20 0.50
DRD1 P21728 7/20 0.48
DRD2 P14416 6/20 0.48
DRD5 P21918 6/20 0.48
DRD3 P35462 6/20 0.48
DRD4 P21917 5/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27757915 0.96 DRD1 (0.52) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL7617252 0.86 F10 (0.45) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL7625300 0.86 F10 (0.48) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL7620197 0.81 DRD1 (0.45) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL25567832 0.78 MAPT (0.58) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL618870 0.76 OPRM1 (0.48) TSHRSIGMAR1TP53
SCHEMBL1513459 0.76 KMT2A (0.46) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL17276366 0.75 ACHE (0.43) TSHRHDAC1HDAC6SIGMAR1TP53
SCHEMBL17276390 0.75 ACHE (0.46) HDAC1HDAC6
SCHEMBL25177736 0.74 BRD4 (0.48) DRD1TSHRSIGMAR1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020019389-A1 Urea derivative useful as an anti-cancer agent and process for preparing same CHACONNE NSI CO., LTD. (KR) 2002-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019389-A1 Urea derivative useful as an anti-cancer agent and process for preparing same UTS2R, SLC14A1, URB2 TUBB4A 2692/4885TUBB 2789/4885TUBA3C 4607/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.