SCHEMBL763015

SCHEMBL763015

Cc1ccc(CCC(=O)NO)cc1

nearest known ligand 0.68

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 14/20 0.67
HDAC2 Q92769 11/20 0.66
HDAC8 Q9BY41 11/20 0.66
HDAC6 Q9UBN7 11/20 0.66
HDAC3 O15379 9/20 0.60
HDAC10 Q969S8 8/20 0.60
HDAC11 Q96DB2 8/20 0.60
HDAC5 Q9UQL6 8/20 0.60
HDAC4 P56524 7/20 0.60
HDAC7 Q8WUI4 7/20 0.60
HDAC9 Q9UKV0 7/20 0.60
NCOR2 Q9Y618 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22190340 0.89 HDAC1 (0.69) HDAC1HDAC2HDAC8HDAC6HDAC3
SCHEMBL10588753 0.85 HDAC1 (0.70) HDAC1HDAC2HDAC8HDAC6HDAC3
SCHEMBL14490981 0.84 CCR5 (0.63) HDAC1HDAC2HDAC8HDAC6HDAC3
SCHEMBL10027984 0.84 HDAC1 (0.67) HDAC1HDAC2HDAC8HDAC6HDAC3
SCHEMBL12507197 0.84 POLB (0.59) HDAC1
SCHEMBL20179119 0.82 HDAC1 (0.68) HDAC1HDAC2HDAC8HDAC6HDAC3
SCHEMBL1981652 0.82 HDAC1 (0.69) HDAC1HDAC2HDAC8HDAC6HDAC3
SCHEMBL8238392 0.82 HDAC8 (0.89) HDAC1HDAC2HDAC8HDAC6HDAC3
SCHEMBL2635132 0.80 HDAC1 (0.67) HDAC1HDAC2HDAC8HDAC6HDAC3
SCHEMBL13486138 0.80 HDAC1 (0.67) HDAC1HDAC2HDAC8HDAC6HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8859048-B2 Selective placement of carbon nanotubes through functionalization INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-10-14 US disclosed
US-8283453-B2 Selective placement of carbon nanotubes through functionalization INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-10-09 US disclosed
US-8138102-B2 Method of placing a semiconducting nanostructure and semiconductor device including the semiconducting nanostructure INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-03-20 US disclosed
US-8084012-B2 Selective placement of carbon nanotubes through functionalization INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2011-12-27 US disclosed
US-20110180777-A1 METHOD OF PLACING A SEMICONDUCTING NANOSTRUCTURE AND SEMICONDUCTOR DEVICE INCLUDING THE SEMICONDUCTING NANOSTRUCTURE INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2011-07-28 US disclosed
US-20100145034-A1 SELECTIVE PLACEMENT OF CARBON NANOTUBES THROUGH FUNCTIONALIZATION INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2010-06-10 US disclosed
US-20100044678-A1 METHOD OF PLACING A SEMICONDUCTING NANOSTRUCTURE AND SEMICONDUCTOR DEVICE INCLUDING THE SEMICONDUCTING NANOSTRUCTURE INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2010-02-25 US disclosed
US-20100041653-A1 COMPOSITION AND METHODS FOR THE DESIGN AND DEVELOPMENT OF METALLO-ENZYME INHIBITORS BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) 2010-02-18 US disclosed
US-20100041653-A1 COMPOSITION AND METHODS FOR THE DESIGN AND DEVELOPMENT OF METALLO-ENZYME INHIBITORS BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) 2010-02-18 US disclosed
US-20090301349-A1 SELECTIVE PLACEMENT OF CARBON NANOTUBES THROUGH FUNCTIONALIZATION INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2009-12-10 US disclosed
US-20080102213-A1 Selective placement of carbon nanotubes through functionalization INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2008-05-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100145034-A1 SELECTIVE PLACEMENT OF CARBON NANOTUBES THROUGH FUNCTIONALIZATION NOXO1, EPCAM, SCO2 HDAC1 2966/4885HDAC2 3581/4885HDAC8 3238/4885
US-20100041653-A1 COMPOSITION AND METHODS FOR THE DESIGN AND DEVELOPMENT OF METALLO-ENZYME INHIBITORS HELZ, MMEL1, GAA HDAC1 28/4885HDAC2 150/4885HDAC8 100/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.