Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | KMO | O15229 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27974145 | 0.90 | MAPT (0.61) | MAPTTDP1KMOLMNAF2 | |
| SCHEMBL7625657 | 0.84 | MAPT (0.52) | MAPTTDP1KMOLMNAF2 | |
| SCHEMBL7636225 | 0.84 | LMNA (0.59) | MAPTTDP1LMNAF2 | |
| SCHEMBL6884851 | 0.83 | LMNA (0.77) | MAPTTDP1LMNAF2 | |
| SCHEMBL7634192 | 0.83 | KMO (0.55) | MAPTTDP1KMOLMNAF2 | |
| SCHEMBL7630725 | 0.82 | MAPT (0.50) | MAPTTDP1KMOLMNAF2 | |
| SCHEMBL29287804 | 0.81 | MAPT (0.63) | MAPTTDP1KMOLMNAHDAC8 | |
| SCHEMBL7633874 | 0.81 | KMO (0.56) | MAPTTDP1KMOLMNAF2 | |
| SCHEMBL1221576 | 0.80 | TSHR (0.67) | MAPTTDP1KMOHDAC8GABRG2 | |
| SCHEMBL29410906 | 0.80 | TSHR (0.67) | MAPTTDP1KMOHDAC8GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1233014-A1 | ASYMMETRIC ORGANIC PEROXIDE, CROSSLINKING AGENT COMPRISING THE SAME, AND METHOD OF CROSSLINKING WITH THE SAME | NOF CORPORATION (JP) | 2002-08-21 | — | — | EP | disclosed |