Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | KMO | O15229 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | F2R | P25116 | 1/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7632824 | 0.86 | MAPT (0.56) | MAPTLMNAF2BCL2 | |
| SCHEMBL7633998 | 0.85 | LMNA (0.65) | TDP1LMNAF2GAA | |
| SCHEMBL7630725 | 0.85 | MAPT (0.50) | MAPTTDP1KMOLMNAF2 | |
| SCHEMBL7630336 | 0.84 | MAPT (0.57) | MAPTTDP1KMOLMNAF2 | |
| SCHEMBL27974145 | 0.84 | MAPT (0.61) | MAPTTDP1KMOLMNAF2 | |
| SCHEMBL7633233 | 0.84 | PTPN11 (0.47) | MAPTTDP1F2R | |
| SCHEMBL7630178 | 0.81 | HPGD (0.49) | MAPTTDP1GAAHDAC8 | |
| SCHEMBL29287804 | 0.79 | MAPT (0.63) | MAPTTDP1KMOLMNAGAA | |
| SCHEMBL7630344 | 0.79 | CES2 (0.56) | — | |
| SCHEMBL7654507 | 0.78 | KMO (0.64) | MAPTTDP1KMOLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1233014-A1 | ASYMMETRIC ORGANIC PEROXIDE, CROSSLINKING AGENT COMPRISING THE SAME, AND METHOD OF CROSSLINKING WITH THE SAME | NOF CORPORATION (JP) | 2002-08-21 | — | — | EP | disclosed |