SCHEMBL7630718

SCHEMBL7630718

C=C[Si](CC)(CC)c1ccc(C(=O)OO[C](C)CC)cc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.33
F2 P00734 1/20 0.33
KDM4E B2RXH2 1/20 0.32
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
ESR1 P03372 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31
ESR2 Q92731 1/20 0.31
CA14 Q9ULX7 1/20 0.31
RAB9A P51151 2/20 0.31
MAPT P10636 2/20 0.31
HPGD P15428 1/20 0.31
RECQL P46063 1/20 0.31
ALDH1A1 P00352 1/20 0.31
NPC1 O15118 1/20 0.31
TP53 P04637 1/20 0.31
POLB P06746 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7630569 0.89 LMNA (0.34) LMNAF2KDM4ECA12CA1
SCHEMBL7636215 0.88 RAB9A (0.34) LMNAF2RAB9AHPGDALDH1A1
SCHEMBL7632193 0.86 HPGD (0.33) LMNAF2CA12CA1CA2
SCHEMBL7631723 0.86 LMNA (0.34) LMNAF2KDM4ECA12CA1
SCHEMBL7633898 0.85 HSD17B3 (0.36) RAB9AMAPTALDH1A1NPC1
SCHEMBL7635551 0.85 ALDH1A1 (0.32) ALDH1A1
SCHEMBL7634060 0.84 NR1H2 (0.38) LMNAF2CA12CA1CA2
SCHEMBL7636859 0.84 LMNA (0.33) LMNAF2CA12CA1CA2
SCHEMBL7629429 0.84 ESR1 (0.35) LMNAF2KDM4ECA12CA1
SCHEMBL7633891 0.83 LMNA (0.33) LMNAF2CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1233014-A1 ASYMMETRIC ORGANIC PEROXIDE, CROSSLINKING AGENT COMPRISING THE SAME, AND METHOD OF CROSSLINKING WITH THE SAME NOF CORPORATION (JP) 2002-08-21 EP disclosed