SCHEMBL7630809

SCHEMBL7630809

CCc1ccc(C(=O)OO[C]2CCCCC2C)cc1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
POLB P06746 1/20 0.47
NPC1 O15118 5/20 0.44
RAB9A P51151 5/20 0.44
ALDH1A1 P00352 4/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
HPGD P15428 1/20 0.44
MAPT P10636 2/20 0.38
PLK1 P53350 1/20 0.37
ADCY1 Q08828 1/20 0.37
LOXL2 Q9Y4K0 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
EPHX1 P07099 1/20 0.36
ADRB2 P07550 1/20 0.36
RXRA P19793 1/20 0.35
RXRB P28702 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7625782 0.91 PLK1 (0.39) MEN1KMT2APOLBNPC1RAB9A
SCHEMBL7630960 0.89 RARB (0.42) ALDH1A1HPGDPLK1
SCHEMBL7634112 0.87 THRA (0.46) MEN1KMT2AALDH1A1MAPTEPHX1
SCHEMBL7633038 0.87 TDP1 (0.41) MEN1KMT2ANPC1RAB9AALDH1A1
SCHEMBL7630926 0.86 THRA (0.47) MEN1KMT2AALDH1A1MAPTEPHX1
SCHEMBL7625291 0.86 NPC1 (0.50) MEN1KMT2APOLBNPC1RAB9A
SCHEMBL7634497 0.86 LMNA (0.46) MEN1KMT2AALDH1A1TDP1
SCHEMBL7633441 0.85 MAPK1 (0.50) KMT2ANPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL7626481 0.84 ALDH1A1 (0.42) MEN1KMT2ARAB9AALDH1A1SMN1; SMN2
SCHEMBL7633653 0.84 NPC1 (0.32) MEN1KMT2APOLBNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1233014-A1 ASYMMETRIC ORGANIC PEROXIDE, CROSSLINKING AGENT COMPRISING THE SAME, AND METHOD OF CROSSLINKING WITH THE SAME NOF CORPORATION (JP) 2002-08-21 EP disclosed