Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7625535 | 1.00 | THRB (0.51) | THRBALDH1A1GAATSHRHPGD | |
| SCHEMBL246239 | 0.96 | THRB (0.55) | THRBALDH1A1GAATSHRHPGD | |
| SCHEMBL11132915 | 0.93 | THRB (0.55) | THRBALDH1A1GAATSHRHPGD | |
| SCHEMBL21154699 | 0.92 | TSHR (0.59) | THRBALDH1A1GAATSHRHPGD | |
| SCHEMBL5899547 | 0.91 | THRB (0.61) | THRBALDH1A1GAATSHRHPGD | |
| SCHEMBL825028 | 0.91 | THRB (0.50) | THRBALDH1A1GAATSHRHPGD | |
| SCHEMBL7631129 | 0.90 | THRB (0.60) | THRBALDH1A1GAATSHRHPGD | |
| SCHEMBL12281676 | 0.90 | THRB (0.60) | THRBALDH1A1GAATSHRHPGD | |
| SCHEMBL19770675 | 0.90 | THRB (0.60) | THRBALDH1A1GAATSHRHPGD | |
| SCHEMBL16804047 | 0.90 | THRB (0.60) | THRBALDH1A1GAATSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5942303-A | CURABLE ADDITION TERPOLYMER BASED ON 2,2-BIS(P-(METH)ACRYLOYL -(P-(METH)ACRYLOYLOXY(ALKYLOXY)N-PHENYL)PROPANES, WHERE N IS 2-5, AND UNSATURATED COMPOUND; IMPACT STRENGTH; LOW SPECIFIC GRAVITY; LIGHTWEIGHT; EYEGLASSES; CONTACT LENSES; LENSES | NOF CORPORATION (JP) | 1999-08-24 | — | — | US | claimed |
| EP-0828167-B1 | Resin composition for polymerization casting and optical material | NOF CORP (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-5942303-A | CURABLE ADDITION TERPOLYMER BASED ON 2,2-BIS(P-(METH)ACRYLOYL -(P-(METH)ACRYLOYLOXY(ALKYLOXY)N-PHENYL)PROPANES, WHERE N IS 2-5, AND UNSATURATED COMPOUND; IMPACT STRENGTH; LOW SPECIFIC GRAVITY; LIGHTWEIGHT; EYEGLASSES; CONTACT LENSES; LENSES | NOF CORPORATION (JP) | 1999-08-24 | — | — | US | disclosed |
| EP-0828167-A2 | Resin composition for polymerization casting and optical material | NOF CORPORATION (JP) | 1998-03-11 | — | — | EP | disclosed |